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465-99-6

" in MedChemExpress (MCE) Product Catalog:

2

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2

Natural
Products

Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-N0256
    Hederagenin
    5+ Cited Publications

    		 COX NF-κB E1/E2/E3 Enzyme Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin can also bind to SKP2, with KD = 67.9 μM. Hederagenin also has preventive potential against alcoholic liver injury .
    Hederagenin
  • HY-N0256R
    Hederagenin (Standard)

    		Reference Standards COX NF-κB Cancer
    Hederagenin (Standard) is the analytical standard of Hederagenin. This product is intended for research and analytical applications. Hederagenin is a triterpenoid saponin with orally active and antitumor activity. Hederagenin can inhibit the expression of iNOS, COX-2, and NF-κB in cells induced by LPS stimulation. Hederagenin also increases ROS production in cancer cells, disrupts mitochondrial membrane potential, and induces apoptosis. Hederagenin also sensitizes cancer cells to Cisplatin (HY-17394) and Paclitaxel (HY-B0015), enhancing induced apoptosis. Hederagenin also has preventive potential against alcoholic liver injury .
    Hederagenin (Standard)

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