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Acetohydroxyacid synthase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetolactate Synthase (ALS) (1) Amino Acid Derivatives (1) Bacterial (1) Fungal (2) Herbicide (4) Reference Standards (1)
By Research Areas:	Infection (3)

Targets Recommended: Acetolactate Synthase (ALS) PGE synthase Thymidylate Synthase Cellulose Synthase ATP Synthase GSK-3 Fatty Acid Synthase (FASN) Glucosylceramide Synthase (GCS) Cyclic GMP-AMP Synthase NO Synthase

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-122950

Harzianic acid	Fungal	Infection
Harzianic acid, a tetramic acid derivative, with activity of antimicrobial, antibiofilm formation and biofilm disaggregation. Harzianic acid interferes with biofilm formation by limiting bacterial iron availability. Harzianic acid is also a selective inhibitor of Acetohydroxyacid synthase (AHAS), the first enzyme in the branched-chain amino acid biosynthetic pathway. Harzianic acid can used for herbicide and fungicide .

HY-B1912

Amidosulfuron	Herbicide	Others
Amidosulfuron is a herbicide. Amidosulfuron targets acetohydroxyacid synthase (AHAS), is highly effective against dicot broad-leaf weeds .

HY-170519

K13787	Bacterial	Infection
K13787 is an acetohydroxyacid synthase (AHAS) inhibitor with antibacterial activity. K13787 has antibacterial activity against a variety of nontuberculous mycobacteria (NTM) and clarithromycin (CLR) resistant strains .

HY-135713

Penoxsulam	Herbicide Acetolactate Synthase (ALS) Fungal	Infection
Penoxsulam is an *acetolactate synthase* (ALS) inhibitor herbicide*. Penoxsulam inhibits Candida auris* acetohydroxyacid synthase (AHAS) with a Ki value of <32 nM. Penoxsulam can be used for postemergence control of annual grasses, sedges, and broadleaf weeds in rice culture. Penoxsulam can be used for the study of Candida auris infections .

HY-B1912R

Amidosulfuron (Standard)	Herbicide Reference Standards	Others
Amidosulfuron (Standard) is the analytical standard of Amidosulfuron. This product is intended for research and analytical applications. Amidosulfuron is a herbicide. Amidosulfuron targets acetohydroxyacid synthase (AHAS), is highly effective against dicot broad-leaf weeds .

HY-162691

DEP-5	Herbicide	Others
DEP-5 is an inhibitor of acetohydroxyacid synthase (AHAS) with an inhibition constant of 39.4 μM. DEP-5 is a diphenyl ether-pyrimidine hybrid with herbicidal activity against the Leptochloa chinensis(L.) Nees .

HY-W097168

Z-DL-His-OH N-Cbz-DL-histidine	Amino Acid Derivatives	Others
Z-DL-His-OH (N-Cbz-DL-histidine) (Compound 14) is a Histidine derivative. Z-DL-His-OH shows no inhibitory effect on the root growth of rapeseed .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Acetohydroxyacid synthase

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