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Results for "

B-form

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Natural
Products

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0511
    Aristolochic acid B
    1 Publications Verification

    Aristolochic acid II

    		 DNA Alkylator/Crosslinker Cancer
    Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510) .
    Aristolochic acid B
  • HY-108882B
    DNase I RNase & Protease free
    25+ Cited Publications

    		 DNA/RNA Synthesis Inflammation/Immunology
    DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune responses. Decreased DNase I activity may be associated with the onset and progression of systemic lupus erythematosus (SLE). DNase I (RNase & Protease free) is a molecular biology-grade DNase I purified by chromatography to remove RNase and protease .
    DNase I RNase & Protease free
  • HY-W001974
    7-Nitroindole

    		DNA/RNA Synthesis Bacterial Others
    7-Nitroindole is a cleavable base analog and Antibacterial agent. 7-Nitroindole inhibits the growth of Lactobacillus arabinosus. 7-Nitroindole is used in studies of light-controlled DNA cleavage and Lactobacillus arabinosus infection .
    7-Nitroindole
  • HY-118138
    NC-182

    		DNA Alkylator/Crosslinker Cancer
    NC-182 is an anti-tumor agent and DNA intercalator with a preference for B-form DNA. NC-182 can also promote the unwinding of Z-form DNA to B-form. NC-182 has a potent inhibitory effect on multidrug-resistant and sensitive tumors.
    NC-182
  • HY-N0511R
    Aristolochic acid B (Standard)

    Aristolochic acid II (Standard)

    		 Reference Standards DNA Alkylator/Crosslinker Cancer
    Aristolochic acid B (Standard) is the analytical standard of Aristolochic acid B (HY-N0511). This product is intended for research and analytical applications. Aristolochic acid B (Aristolochic Acid II) is an orally active major component of aristolochic acid (AA). Aristolochic acid B can be isolated from plants of the genus Aristolochica. Aristolochic acid B forms DNA adducts. Aristolochic acid B is mutagenic. Aristolochic acid B exhibits a greater carcinogenic risk in vivo than Aristolochic acid I (HY-N0510) .
    Aristolochic acid B (Standard)
  • HY-E71081
    (E,E)-Germacrene B synthase

    		Biochemical Assay Reagents Others
    (E,E)-Germacrene B synthase (EC 4.2.3.71) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase ( (E,E)-Germacrene-B-forming) .
    (E,E)-Germacrene B synthase
  • HY-E71107
    (S)-2-Hydroxy-acid oxidase

    		Biochemical Assay Reagents Others
    (S)-2-Hydroxy-acid oxidase (EC 1.1.3.15) is a flavoprotein (FMN) . Exists as two major isoenzymes; the A form preferentially oxidizes short-chain aliphatic hydroxy acids; the B form preferentially oxidizes long-chain and aromatic hydroxy acids.
    (S)-2-Hydroxy-acid oxidase
  • HY-182769
    TRβ agonist-4

    		Thyroid Hormone Receptor Inflammation/Immunology
    TRβ agonist-4 is an orally bioavailable, liver-targeted selective agonist of hTHR-β (EC50=6.0 nM), with a 105.3-fold selectivity over THR-α. TRβ agonist-4 exists in multiple crystal forms, including Form A, Form B, Form C, Form D, Form E, as well as an amorphous form. TRβ agonist-4 can be used for research related to non-alcoholic steatohepatitis (NASH) .
    TRβ agonist-4
  • HY-181740
    GCB-27b

    		CD1 Cancer
    GCB-27b is an immunostimulant that binds to CD1d. GCB-27b forms a stable and long-lasting complex with CD1d, which is presented to the TCR of NKT cells to drive immune responses. GCB-27b induces a Th1-skewed immune response in *Mus musculus*, resulting in high expression of IFN−γ with restricted IL-4 levels. GCB-27b is applicable to research related to lung metastasis of melanoma .
    GCB-27b
  • HY-181085
    RD0448

    		DYRK Neurological Disease Inflammation/Immunology Cancer
    RD0448 is a potent inhibitor of DYRK1A, DYRK1B, and DYRK2. RD0448 selectively targets the non-native (folded intermediate) state of DYRK1A and DYRK1B. The binding site of RD0448 is hidden in the native state of DYRK1A and DYRK1B, and as a stabilizing binder, it binds tightly to both DYRK1A and DYRK1B, forming a stable complex with slow dissociation kinetics. In contrast, RD0448 targets the native state of DYRK2 without selectivity between its native and non-native states, acting as a weak binder with weaker binding affinity to DYRK2 and forming a rapidly dissociating complex .
    RD0448

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