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Results for "

BCAT

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (4) Inflammation/Immunology (1) Metabolic Disease (3) Neurological Disease (2)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

BCAT-IN-1	Others	Metabolic Disease
BCAT-IN-1 is a potent, selective and orally active inhibitor of BCATm, with a pIC₅₀ of 7.3. BCAT-IN-1 shows 100-fold selectivity for BCATm over BCATc (pIC₅₀=5.4). BCAT-IN-1 can be used for the research of metabolic diseases .

BCAT-IN-2 1 Publications Verification	Others	Metabolic Disease
BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC₅₀ of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC₅₀=6.6). BCAT-IN-2 can be used for the research of obesity and dislipidema .

BCAT-IN-4	Others	Neurological Disease
BCAT-IN-4 (Compound 1) is a *BCAT* inhibitor. BCAT-IN-4 exhibits a moderate ability to inhibit hBCATc with IC₅₀ value of 2.35 μM. BCAT-IN-4 can be used for the research of neurodegenerative diseases .

BCAT1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BCAT1 Human Pre-designed siRNA Set A contains three designed siRNAs for BCAT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BCAT1 Human Pre-designed siRNA Set A BCAT1 Human Pre-designed siRNA Set A

BCAT2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BCAT2 Human Pre-designed siRNA Set A contains three designed siRNAs for BCAT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BCAT2 Human Pre-designed siRNA Set A BCAT2 Human Pre-designed siRNA Set A

BCATc Inhibitor 2 2 Publications Verification	Others	Neurological Disease
BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC₅₀s of 0.2 μM, 0.8 μM and 3.0 μM for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm .

BAY-069 1 Publications Verification	Others	Cancer
BAY-069 is a potent branched-chain amino acid transaminases 1 (BCAT1) and *BCAT2* inhibitor with IC₅₀ values of 31 nM and 153 nM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used tor research anticancer .

BAY-252	Others	Cancer
BAY-252 is a potent branched-chain amino acid transaminases 1 (BCAT1) and *BCAT2* inhibitor with IC₅₀s of 2 μM and 2 μM, respectively. BAY-069 also can be used as a chemical probe. BAY-069 can be used for the research of cancer .

EGR240	Others	Inflammation/Immunology Cancer
EGR240 is a branched-chain amino acid aminotransferase 1 (BCAT1) inhibitor. EGR240 can be used for the research of cancer, rheumatoid arthritis, and bone disease .

BAY-771	Others	Metabolic Disease Cancer
BAY-771, a structurally close pyrimidinedione, is a chemical probe with good lead-like properties and high permeability in Caco-2 cells (no hint of efflux). BAY-771 shows very weak inhibitory activity in the BCAT1 biochemical assay and no activity in BCAT2. BAY-771 can be used as a negative control of HY-148242 BAY-069. BAY-771 can be used for the research of tumor metabolism .

Cat. No.	Compare	Product Name	Species	Source

	BCAT2 Protein, Human (His, Strep) BCAT2; Branched-chain-amino-acid aminotransferase; mitochondrial; BCAT(m); Placental protein 18; PP18	Human	E. coli
	Various studies have demonstrated that the BCAT2 protein plays a critical role in cellular processes as it catalyzes the initial reactions in the catabolism of the essential branched-chain amino acids leucine, isoleucine, and valine. This enzyme activity is essential for the breakdown of these amino acids, contributing to metabolic processes necessary for energy production and nitrogen balance. BCAT2 Protein, Human (His, Strep) is the recombinant human-derived BCAT2 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of BCAT2 Protein, Human (His, Strep) is 365 a.a., .

	BCAT1 Protein, Human BCAT1; Branched-chain-amino-acid aminotransferase; cytosolic; BCAT(c); Protein ECA39	Human	E. coli
	The BCAT1 protein plays a key role in cellular processes as it catalyzes the initial reactions in the catabolism of the essential branched-chain amino acids leucine, isoleucine, and valine. This enzyme activity is essential for the breakdown of these amino acids, contributing to metabolic pathways necessary for energy production and nitrogen balance. BCAT1 Protein, Human is the recombinant human-derived BCAT1 protein, expressed by E. coli , with tag free. The total length of BCAT1 Protein, Human is 385 a.a., .

	BCAT1 Protein, Human (His, Strep) BCAT1; Branched-chain-amino-acid aminotransferase; cytosolic; BCAT(c); Protein ECA39	Human	E. coli
	The BCAT1 protein plays a key role in cellular processes as it catalyzes the initial reactions in the catabolism of the essential branched-chain amino acids leucine, isoleucine, and valine. This enzyme activity is essential for the breakdown of these amino acids, contributing to metabolic pathways necessary for energy production and nitrogen balance. BCAT1 Protein, Human (His, Strep) is the recombinant human-derived BCAT1 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of BCAT1 Protein, Human (His, Strep) is 385 a.a., .

	BCAT2 Protein, Human BCAT2; Branched-chain-amino-acid aminotransferase; mitochondrial; BCAT(m); Placental protein 18; PP18	Human	E. coli
	Various studies have demonstrated that the BCAT2 protein plays a critical role in cellular processes as it catalyzes the initial reactions in the catabolism of the essential branched-chain amino acids leucine, isoleucine, and valine. This enzyme activity is essential for the breakdown of these amino acids, contributing to metabolic processes necessary for energy production and nitrogen balance. BCAT2 Protein, Human is the recombinant human-derived BCAT2 protein, expressed by E. coli , with tag free. The total length of BCAT2 Protein, Human is 365 a.a., .


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