BCAT2 Protein, Human (His, Strep)

Various studies have demonstrated that the BCAT2 protein plays a critical role in cellular processes as it catalyzes the initial reactions in the catabolism of the essential branched-chain amino acids leucine, isoleucine, and valine. This enzyme activity is essential for the breakdown of these amino acids, contributing to metabolic processes necessary for energy production and nitrogen balance. BCAT2 Protein, Human (His, Strep) is the recombinant human-derived BCAT2 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of BCAT2 Protein, Human (His, Strep) is 365 a.a., .

BCAT2 (Branched-chain amino acid transaminase 2) plays a key role in the catabolism of the essential branched-chain amino acids leucine, isoleucine, and valine. It catalyzes the first reaction in this process, involving the reversible transamination of these amino acids to their respective branched-chain alpha-keto acids. This enzymatic activity is crucial for regulating the levels of branched-chain amino acids and their metabolites, which are involved in various physiological processes, including energy metabolism and protein synthesis. Additionally, BCAT2 may function as a transporter for branched-chain alpha-keto acids, contributing to their cellular transport. It has to succinctly outline BCAT2's central role in branched-chain amino acid catabolism and suggests its potential involvement in the intracellular transport of related metabolites.

Human

E. coli

N-Strep;N-6*His

O15382 (A28-V392)

587

Approximately 44.4 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Solution

Supplied as a 0.22 μm filtered solution of 50 mM Tris-HCl, pH7.5, 200 mM NaCl, 20% glycerol.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.