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Results for "

CCS

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-111784
    Inobrodib
    4 Publications Verification

    CCS1477

    		 Epigenetic Reader Domain Cancer
    Inobrodib (CCS1477) is an orally active, potent, and selective inhibitor of the p300/CBP bromodomain. Inobrodib binds to p300 and CBP with Kd values of 1.3 and 1.7 nM, respectively, and with 170/130-fold selectivity compared with BRD4 with a Kd of 222 nM. CCS1477 inhibits cell proliferation in prostate cancer cell lines and decreases androgen receptor (AR)- and C-MYC-regulated gene expression .
    Inobrodib
  • HY-107636
    DC_AC50
    1 Publications Verification

    		 Apoptosis Cancer
    DC_AC50 is a dual inhibitor of Atox1 and CCS (copper chaperones). Inhibiting intracellular copper chaperones as a means of reducing/preventing acquired chemotherapy resistance .
    DC_AC50
  • HY-RS02176
    CCS Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CCS Human Pre-designed siRNA Set A contains three designed siRNAs for CCS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CCS Human Pre-designed siRNA Set A
    CCS Human Pre-designed siRNA Set A
  • HY-147373
    DA-PROTAC

    		PROTACs Ligands for E3 Ligase Cancer
    DA-PROTAC is a potent PROTAC degrader of copper ion-transport proteins Atox1 and CCS. DA-PROTAC can bind both Atox1 and CCS proteins, and the complex can be bound to E3 ligase, leading to increased levels of ubiquitination of Atox1 and CCS and degradation of Atox1 and CCS proteins via the proteasome pathway. DA-PROTAC can be used for triple negative breast cancer research .
    DA-PROTAC
  • HY-160005
    LMP517

    NSC 781517

    		 Topoisomerase Cancer
    LMP517 (NSC 781517) a indenoisoquinoline, is a potent a dual TOP1 and TOP2 inhibitor. LMP517 shows better antitumor activity than its parent compound LMP744 (HY-U00248) against H82 (Small Cell Lung Cancer) xenografts. LMP517 induces TOP1 cleavage complexes (TOP1ccs) and TOP2ccs .
    LMP517

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