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CD28

" in MedChemExpress (MCE) Product Catalog:
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  • HY-P74309
    CD28 Protein, Rat (HEK293, His)

    CD28; T-cell-specific surface glycoprotein CD28; Tp44

    		 Rat HEK293
    CD28 Protein activates T-cells, promoting cell proliferation, cytokine production, and T-cell survival. It collaborates with TCR/CD3 ligation and CD40L costimulation to boost IL4 and IL10 production in T-cells. CD28 Protein forms a disulfide-linked homodimer and interacts with DUSP14. It also binds to CD80/B7-1 and CD86/B7-2/B70, and interacts with GRB2 (By similarity). CD28 Protein, Rat (HEK293, His) is the recombinant rat-derived CD28 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD28 Protein, Rat (HEK293, His) is 130 a.a., with molecular weight of ~30-36 kDa.
  • HY-P74310
    CD28 Protein, Rat (HEK293, Fc)

    CD28; T-cell-specific surface glycoprotein CD28; Tp44

    		 Rat HEK293
    CD28 Protein activates T-cells, promoting cell proliferation, cytokine production, and T-cell survival. It collaborates with TCR/CD3 ligation and CD40L costimulation to boost IL4 and IL10 production in T-cells. CD28 Protein forms a disulfide-linked homodimer and interacts with DUSP14. It also binds to CD80/B7-1 and CD86/B7-2/B70, and interacts with GRB2 (By similarity). CD28 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD28 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD28 Protein, Rat (HEK293, Fc) is 130 a.a., with molecular weight of ~42 kDa.
  • HY-P74215
    CTLA-4 Protein, Rat (HEK293, His)

    Cytotoxic T-lymphocyte associated protein 4; CTLA4; CD152

    		 Rat HEK293
    CTLA-4 protein inhibits T-cell responses by binding strongly to CD80 and CD86 receptors, surpassing CD28. This affinity allows CTLA-4 to effectively regulate T-cell activation and immune responses. The balance between inhibitory and stimulatory signals controlled by CTLA-4 and its ligands modulates T-cell-mediated immune reactions. CTLA-4 Protein, Rat (HEK293, His) is the recombinant rat-derived CTLA-4 protein, expressed by HEK293 , with C-His labeled tag. The total length of CTLA-4 Protein, Rat (HEK293, His) is 161 a.a., with molecular weight of 21-30 kDa.
  • HY-P73492
    B7-2/CD86 Protein, Rat (250a.a, HEK293, His)

    Activation B7-2 antigen; B70; BU63; CD86; CD28LG2

    		 Rat HEK293
    B7-2/CD86 Protein is an immunoglobulin superfamily (IgSF) member with their extracellular regions consisting of one amino-terminal Ig variable-like (IgV) and one membrane proximal Ig constant-like (IgC) domain. CD86, a costimulatory ligand expressed on antigen-presenting cells (APC), binds the homologous T cell receptors CD28 and CTLA-4, and trigger costimulatory signals important for optimal T cell activation. CD86 is an immune checkpoint protein expressed on the surface of tumor cells and infiltrative tumor lymphocytes. B7-2/CD86 Protein, Rat (250a.a, HEK293, His) is the recombinant rat-derived B7-2/CD86 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-2/CD86 Protein, Rat (250a.a, HEK293, His) is 250 a.a., with molecular weight of 40-70 kDa.
  • HY-P74398
    B7-1/CD80 Protein, Rat (HEK293, Fc)

    T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; B7; CD80; CD28LG; LAB7

    		 Rat HEK293
    B7-1/CD80, a type I membrane protein, is a member of the B7 family, with an extracellular immunoglobulin constant-like domain and a variable-like domain required for receptor binding. CD80 is also a transmembrane glycoprotein and a member of the Ig superfamily. CD80 has a crucial role in modulating T-cell immune function as a checkpoint protein at the immunological synapse. Its binding to CD28 or CTLA-4 receptors is integral to inducing T-cell proliferation and cytokine production. B7-1/CD80 Protein, Rat (HEK293, Fc) is the recombinant rat-derived B7-1/CD80 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of B7-1/CD80 Protein, Rat (HEK293, Fc) is 248 a.a., with molecular weight of ~51 kDa.
  • HY-P74216
    CTLA-4 Protein, Rat (HEK293, Fc)

    Cytotoxic T-lymphocyte associated protein 4; CTLA4; CD152

    		 Rat HEK293
    CTLA-4 protein inhibits T-cell responses by binding strongly to CD80 and CD86 receptors, surpassing CD28. This affinity allows CTLA-4 to effectively regulate T-cell activation and immune responses. The balance between inhibitory and stimulatory signals controlled by CTLA-4 and its ligands modulates T-cell-mediated immune reactions. CTLA-4 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CTLA-4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CTLA-4 Protein, Rat (HEK293, Fc) is 161 a.a., with molecular weight of ~40.5 kDa.

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