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Results for "

CINV

" in MCE Product Catalog:

By Targets:	5-HT Receptor (4) Cytochrome P450 (1) Neurokinin Receptor (4)
By Research Areas:	Cancer (3) Cardiovascular Disease (3) Endocrinology (3) Neurological Disease (5)

8

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas

Azasetron hydrochloride Y-25130 hydrochloride	5-HT Receptor	Neurological Disease
Azasetron (Y-25130) hydrochloride, a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist. Azasetron is used in the study for Chemotherapy-induced nausea and vomiting (CINV).

Casopitant mesylate GW679769B	Neurokinin Receptor Cytochrome P450	Neurological Disease Cancer
Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of substance P. Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).

Palonosetron-d3 hydrochloride	5-HT Receptor	Cardiovascular Disease
Palonosetron-d₃ (hydrochloride) is the deuterium labeled Palonosetron hydrochloride. Palonosetron hydrochloride is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV)[1][2].

Fosaprepitant L-758298	Neurokinin Receptor	Neurological Disease Endocrinology
Fosaprepitant (L-785298) is a prodrug of Aprepitant (HY-10052). Fosaprepitant is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV).

Fosaprepitant dimeglumine MK-0517; L785298	Neurokinin Receptor	Neurological Disease Endocrinology Cancer
Fosaprepitant dimeglumine (MK-0517) is a prodrug of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV).

Fosaprepitant-d4 dimeglumine MK-0517-d₄; L785298-d₄	Neurokinin Receptor	Neurological Disease Endocrinology Cancer
Fosaprepitant-d₄ (dimeglumine) is deuterium labeled Fosaprepitant (dimeglumine). Fosaprepitant dimeglumine (MK-0517) is a prodrug of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV)[1].

Palonosetron hydrochloride	5-HT Receptor	Cardiovascular Disease
Palonosetron hydrochloride is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

HY-A0018

Palonosetron
5-HT Receptor Cardiovascular Disease

Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

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