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Cystathionine γ-lyase (CTH)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bcl-2 Family (1) Cadherin (1) Caspase (1) NF-κB (1)
By Research Areas:	Cancer (1) Neurological Disease (1)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-181717

TKL002	NF-κB Apoptosis Cadherin Caspase Bcl-2 Family	Neurological Disease Cancer
TKL002 is a blood-brain barrier-permeable inhibitor of the CTH/H₂S/NF-κB/EMT signaling axis. TKL002 induces G₂/M phase cell cycle arrest and apoptosis in glioblastoma cells. TKL002 inhibits the migration and invasion of glioblastoma cells by upregulating E-cadherin and downregulating N-cadherin and vimentin. TKL002 is applicable to relevant research on glioblastoma .

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HY-P70025

	Cystathionine gamma-lyase/CTH Protein, Human rHuCystathionine gamma-lyase/CTH; Cystathionine Gamma-lyase; Cysteine-Protein Sulfhydrase; Gamma-Cystathionase; CTH	Human	E. coli
	CTH protein is a cysteine protein sulfatase that catalyzes the final step of the transsulfuration pathway in a PLP-dependent manner. Cystathionine gamma-lyase/CTH Protein, Human is the recombinant human-derived Cystathionine gamma-lyase/CTH protein, expressed by E. coli , with tag free.

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HY-P82707

	Cystathionase Antibody (YA2452) CTH; Cystathionine gamma lyase; Cysteine desulfhydrase; Gamma cystathionase; Homoserine deaminase	WB, IP	Human
	Cystathionase Antibody (YA2452) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cystathionase.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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