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Results for "

GCA

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

2

Recombinant Proteins

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100540
    Golgicide A
    3 Publications Verification

    GCA
    Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 . Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .
    Golgicide A
  • HY-100540B
    Golgicide A-2

    GCA-2

    		 Flavivirus Dengue virus Enterovirus Infection
    Golgicide A-2 (GCA-2), a Golgicide A (GCA) derivative, is the most active enantiomer of GCA. Golgicide A-2 displays high selectivity and efficiency in killing An. stephensi larvae and can be used for the research of dengue virus related diseases .
    Golgicide A-2
  • HY-100540C
    Golgicide A-1

    GCA-1

    		 Others Infection
    Golgicide A-1 (GCA-1) is a less active cis-diastereomer of Golgicide A (GCA). Golgicide A-1 weakly inhibits mosquito reproduction .
    Golgicide A-1
  • HY-116528
    GCA-186

    		HIV Infection
    GCA-186 is a potent anti-HIV-1 agent. GCA-186 is highly active against both wild type and mutated HIV-1 strains with EC50s of 1, 180, 1, and 40 nM for IIIB, IIIB-R(Y181C), NL4-3 and NL4-3K103N of HIV-1 strains, respectively .
    <em>GCA</em>-186
  • HY-RS05317
    GCA Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    GCA Human Pre-designed siRNA Set A contains three designed siRNAs for GCA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    GCA Human Pre-designed siRNA Set A
    GCA Human Pre-designed siRNA Set A
  • HY-100540A
    (Rac)-Golgicide A

    (Rac)-GCA

    		 Enterovirus Infection
    (Rac)-Golgicide A ((Rac)-GCA) is a racemate of Golgicide A. Golgicide A (GCA) is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1 .Golgicide A drastically reduced replication of coxsackievirus B3 (CVB3) and other human enterovirus species .
    (Rac)-Golgicide A
  • HY-148100
    Emapticap pegol

    NOX-E36

    		 Others Inflammation/Immunology Cancer
    Emapticap pegol is a inhibitor of pro-inflammatory chemokine C-C motif-ligand 2 (CCL2). Emapticap pegol is a 40-nucleotide oligonucleotide aptamer, displays different Spiegelmers (L-RNA aptamer) isform in human (NOX-E36) and mouse (mNOX-E36) .
    Emapticap pegol
  • HY-142118
    Trabedersen

    AP 12009

    		 TGF-beta/Smad Cancer
    Trabedersen (AP 12009) is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen can be used for the study of malignant brain tumors and other solid tumors overexpressing TGF-β2, such as those of the skin, pancreas and colon .
    Trabedersen
  • HY-145728
    Alicaforsen

    ISIS-2302

    		 Integrin Inflammation/Immunology
    Alicaforsen is a 20-base antisense oligonucleotide inhibiting ICAM-1 production, which is an important adhesion molecule involved in leukocyte migration and trafficking to the site of inflammation.
    Alicaforsen
  • HY-150213
    ODN BW001

    		CDK Inflammation/Immunology
    ODN BW001 is an oligodeoxynucleotide (ODN). ODN BW001 plays a regulatory role in the proliferation and activation of osteoblast .
    ODN BW001
  • HY-132596
    Tivanisiran

    SYL1001

    		 Small Interfering RNA (siRNA) TRP Channel Neurological Disease
    Tivanisiran (SYL1001) is a siRNA used for the study of dry eye disease. Tivanisiran was designed to silence transient receptor potential vanilloid 1 (TRPV1) .
    Tivanisiran
  • HY-143230
    Custirsen

    OGX-011

    		 Apoptosis Cancer
    Custirsen is a highly specific antisense oligonucleotide that inhibits the production of clusterin , an antiapoptotic protein that is upregulated in response to chemotherapy and that confers treatment resistance.
    Custirsen

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