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Results for "

HG-2

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

2

Fluorescent Dye

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103641
    (2R)-Octyl-α-hydroxyglutarate
    2 Publications Verification

    (2R)-Octyl-2-HG

    		 Others Cancer
    (2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a modified form of D-isomer 2-Hydroxyglutarate.
    (<em>2</em>R)-Octyl-α-hydroxyglutarate
  • HY-103641A
    (2S)-Octyl-α-hydroxyglutarate
    1 Publications Verification

    (2S)-Octyl-2-HG

    		 Others Cancer
    (2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.
    (<em>2</em>S)-Octyl-α-hydroxyglutarate
  • HY-P5706
    HG2

    		Bacterial Infection Inflammation/Immunology
    HG2 is a fast-acting antimicrobial peptide. HG2 shows anti-biofilm and anti-inflammatory activities. HG2 is active against Gram-positive pathogens, especially against MRSA strains (MIC: 16-32?μg/mL). HG2 can bind to bacterial lipids and reduces ATP concentration in S. aureus MRSA USA300 cells .
    <em>HG2</em>
  • HY-D1750
    Rhodamine B thiolactone

    		Fluorescent Dye Others
    Rhodamine B thiolactone is a high-sensitive Hg 2+ indicator used for measuring Hg 2+ concentration.
    Rhodamine B thiolactone
  • HY-D1549
    o-Pah

    		Fluorescent Dye Others
    o-Pah is a BODIPY derivative with an -NH2 and -OH substituted meso-Ph group. o-Pah exhibits metal-induced J-aggregation in the presence of Cu 2+ and a specific fluorescence enhancement for Hg 2+ (Ex/Em=483/(495-600) nM) .
    o-Pah
  • HY-129079
    TFMB-(R)-2-HG
    1 Publications Verification

    		 Others Cancer
    TFMB-(R)-2-HG, a cell membrane-permeable version of (R)-2-HG, is a carcinogenic factor in Acute myeloid leukemia (AML). TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cells differentiation in response to estrogen withdrawal .
    TFMB-(R)-<em>2</em>-HG
  • HY-143234
    mIDH1-IN-1

    		Isocitrate Dehydrogenase (IDH) Cancer
    mIDH1-IN-1 (compound 43) is a potent and selective mIDH1 (mutant isocitrate dehydrogenases 1) inhibitor, with an IC50 of 961.5 nM. mIDH1-IN-1 potently inhibits intracellular 2-HG (2-hydroxyglutarate) production in HT1080 cells, with an EC50 of 208.6 ± 8.0 nM. mIDH1-IN-1 shows a significant anti-proliferation activity on IDH1 mutant-U-87 cells, with an IC50 of 41.8 nM. mIDH1-IN-1 is an antitumor agent, and can be used for IDH1 mutated solid tumors research .
    mIDH1-IN-1
  • HY-104042
    Vorasidenib
    3 Publications Verification

    AG-881

    		 Isocitrate Dehydrogenase (IDH) Cancer
    Vorasidenib (AG-881) is an orally available, brain penetrant second-generation dual mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2) inhibitor. Vorasidenib (AG-881) exhibits nanomolar inhibition of (D)-2-hydroxyglutarate (D-2-HG), and the IC50 ranges of 0.04~22 nM against IDH1 R132C, IDH1 R132G, IDH1 R132H and IDH1 R132S and 7~14 nM against IDH2 R140Q and 130 nM against IDH2 R172K [2].
    Vorasidenib

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