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(2S)-Octyl-α-hydroxyglutarate (Synonyms: (2S)-Octyl-2-HG)

Cat. No.: HY-103641A Purity: 98.60% ee.: 100.00%
Handling Instructions

(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.

For research use only. We do not sell to patients.

(2S)-Octyl-α-hydroxyglutarate Chemical Structure

(2S)-Octyl-α-hydroxyglutarate Chemical Structure

CAS No. : 1391194-64-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 241 In-stock
Estimated Time of Arrival: December 31
1 mg USD 84 In-stock
Estimated Time of Arrival: December 31
5 mg USD 252 In-stock
Estimated Time of Arrival: December 31
10 mg USD 432 In-stock
Estimated Time of Arrival: December 31
25 mg USD 972 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (2S)-Octyl-α-hydroxyglutarate:

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Description

(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a modified form of S-isomer 2-Hydroxyglutarate.

In Vitro

Treatment of IDH1-WT HeLa cells with (2S)-Octyl-α-hydroxyglutarate, a modified form of 2-Hydroxyglutarate with high cellular uptake, results in a dose-dependent increase in DSBs in log-phase cells[1].

Molecular Weight

260.33

Formula

C₁₃H₂₄O₅

CAS No.

1391194-64-1

SMILES

O=C(OCCCCCCCC)[[email protected]@H](O)CCC(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (384.13 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8413 mL 19.2064 mL 38.4128 mL
5 mM 0.7683 mL 3.8413 mL 7.6826 mL
10 mM 0.3841 mL 1.9206 mL 3.8413 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (9.60 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (9.60 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (9.60 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 98.60% ee.: 100.00%

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Product Name:
(2S)-Octyl-α-hydroxyglutarate
Cat. No.:
HY-103641A
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