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ICOS

" in MedChemExpress (MCE) Product Catalog:
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  • HY-P72619
    ICOS Protein, Mouse (HEK293, His)

    Inducible T-cell costimulator; CD278; AILIM; CVID1; ICOS

    		 Mouse HEK293
    ICOS proteins optimize T cell responses to foreign antigens, promoting proliferation, lymphokine secretion, upregulation of cell-cell interaction molecules, and efficient B cell antibody secretion. ICOS is essential for efficient communication of T cells and B cells and for normal antibody responses to T cell-dependent antigens. ICOS Protein, Mouse (HEK293, His) is the recombinant mouse-derived ICOS protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ICOS Protein, Mouse (HEK293, His) is 122 a.a., with molecular weight of 16-30 kDa.
  • HY-P78673
    ICOS Protein, Mouse (C137S, C138S, HEK293, Fc)

    ICOS; CD278; AILIM; Inducible T-cell costimulator

    		 Mouse HEK293
    ICOS protein optimizes essential T-cell responses to foreign antigens, fostering proliferation, lymphokine secretion, up-regulation of cell-cell interaction molecules, and effective B-cell antibody secretion. Crucial for efficient T and B-cell communication, ICOS is vital for normal antibody responses to T-cell dependent antigens. While it doesn't increase interleukin-2 production, it superinduces interleukin-10 synthesis. Moreover, ICOS prevents apoptosis in pre-activated T-cells and plays a critical role in CD40-mediated immunoglobulin class switching. It exists as a homodimer connected by disulfide bonds. ICOS Protein, Mouse (C137S, C138S, HEK293, Fc) is the recombinant mouse-derived ICOS protein, expressed by HEK293 , with C-hFc labeled tag and C137S, C138S mutation. The total length of ICOS Protein, Mouse (C137S, C138S, HEK293, Fc) is 124 a.a., with molecular weight of 40-52 kDa.
  • HY-P76397
    ICOS Protein, Mouse (Biotinylated, HEK293, Fc-Avi)

    Inducible T-cell costimulator; CD278; AILIM; CVID1; ICOS

    		 Mouse HEK293
    ICOS proteins optimize T cell responses to foreign antigens, promoting proliferation, lymphokine secretion, upregulation of cell-cell interaction molecules, and efficient B cell antibody secretion. ICOS is essential for efficient communication of T cells and B cells and for normal antibody responses to T cell-dependent antigens. ICOS Protein, Mouse (Biotinylated, HEK293, Fc-Avi) is the recombinant mouse-derived ICOS protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of ICOS Protein, Mouse (Biotinylated, HEK293, Fc-Avi) is 142 a.a., with molecular weight of ~42.4 KDa.
  • HY-P78307
    ICOS Protein, Mouse (124a.a, HEK293, Fc)

    AILIM; CD278; CRP-1; CVID1; ICOS; MGC39850

    		 Mouse HEK293
    ICOS proteins optimize T cell responses to foreign antigens, promoting proliferation, lymphokine secretion, upregulation of cell-cell interaction molecules, and efficient B cell antibody secretion. ICOS is essential for efficient communication of T cells and B cells and for normal antibody responses to T cell-dependent antigens. ICOS Protein, Mouse (124a.a, HEK293, Fc) is the recombinant mouse-derived ICOS protein, expressed by HEK293 , with C-hFc labeled tag. The total length of ICOS Protein, Mouse (124a.a, HEK293, Fc) is 124 a.a., with molecular weight of 65-80 kDa.
  • HY-P78306
    ICOS Protein, Mouse (C137S, C138S, HEK293, His)

    AILIM; CD278; CRP-1; CVID1; ICOS; MGC39850

    		 Mouse HEK293
    ICOS protein optimizes essential T-cell responses to foreign antigens, fostering proliferation, lymphokine secretion, up-regulation of cell-cell interaction molecules, and effective B-cell antibody secretion. Crucial for efficient T and B-cell communication, ICOS is vital for normal antibody responses to T-cell dependent antigens. While it doesn't increase interleukin-2 production, it superinduces interleukin-10 synthesis. Moreover, ICOS prevents apoptosis in pre-activated T-cells and plays a critical role in CD40-mediated immunoglobulin class switching. It exists as a homodimer connected by disulfide bonds. ICOS Protein, Mouse (C137S, C138S, HEK293, His) is the recombinant mouse-derived ICOS protein, expressed by HEK293 , with C-His labeled tag and C137S, C138S mutation. The total length of ICOS Protein, Mouse (C137S, C138S, HEK293, His) is 124 a.a., with molecular weight of 27-38 kDa.
  • HY-P73120
    B7-H2/ICOSLG Protein, Mouse (HEK293, His)

    ICOS ligand; B7-H2; ICOSLG; LICOS; B7RP-1; CD275

    		 Mouse HEK293
    B7-H2/ICOSLG, a crucial ligand for T-cell receptor ICOS, mediates immune responses. It serves as a costimulatory signal, promoting T-cell and B-cell proliferation, cytokine secretion, and plasma cell differentiation. Beyond immune activation, it may influence local tissue responses during inflammation and modulate secondary immune responses. During pregnancy, B7-H2/ICOSLG favors an immunoprotective Th2 phenotype in maternal T-cells. It also interacts with CTLA4, contributing to intricate regulatory pathways of immune function. B7-H2/ICOSLG Protein, Mouse (HEK293, His) is the recombinant mouse-derived B7-H2/ICOSLG protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-H2/ICOSLG Protein, Mouse (HEK293, His) is 233 a.a., with molecular weight of ~40-52 kDa.
  • HY-P73119
    B7-H2/ICOSLG Protein, Mouse (HEK293, His-Fc)

    ICOS ligand; B7-H2; ICOSLG; LICOS; B7RP-1; CD275

    		 Mouse HEK293
    B7-H2/ICOSLG is an important ligand of the T cell receptor ICOS and mediates immune responses. It acts as a costimulatory signal, promoting T and B cell proliferation, cytokine secretion, and plasma cell differentiation. B7-H2/ICOSLG Protein, Mouse (HEK293, His-Fc) is the recombinant mouse-derived B7-H2/ICOSLG protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of B7-H2/ICOSLG Protein, Mouse (HEK293, His-Fc) is 233 a.a., with molecular weight of 75-85 kDa.

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