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Results for "

LEE+011

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15777
    Ribociclib
    Maximum Cited Publications
    80 Publications Verification

    LEE011

    CDK Neurological Disease Cancer
    RRibociclib (LEE011) is an ATP-competitive and orally active CDK4/6 inhibitor that crosses the blood-brain barrier with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
    Ribociclib
  • HY-15777A
    Ribociclib hydrochloride
    Maximum Cited Publications
    80 Publications Verification

    LEE011 hydrochloride

    CDK Neurological Disease Cancer
    RRibociclib (LEE011) hydrochloride is an ATP-competitive and orally active CDK4/6 inhibitor that crosses the blood-brain barrier with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
    Ribociclib hydrochloride
  • HY-15777B
    Ribociclib succinate
    Maximum Cited Publications
    80 Publications Verification

    LEE011 succinate

    CDK Neurological Disease Cancer
    RRibociclib (LEE011) succinate is an ATP-competitive and orally active CDK4/6 inhibitor that crosses the blood-brain barrier with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
    Ribociclib succinate
  • HY-15777S

    LEE011-d6

    CDK Cancer
    Ribociclib-d6 (LEE011-d6) is a deuterium labeled Ribociclib (HY-15777). Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
    Ribociclib-d6
  • HY-15777C
    Ribociclib succinate hydrate
    Maximum Cited Publications
    80 Publications Verification

    LEE011 succinate hydrate

    CDK Cancer
    RRibociclib (LEE011) succinate hydrate is an ATP-competitive and orally active CDK4/6 inhibitor that crosses the blood-brain barrier with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
    Ribociclib succinate hydrate
  • HY-15777R

    LEE011 (Standard)

    Reference Standards CDK Cancer
    Ribociclib (Standard) is the analytical standard of Ribociclib. This product is intended for research and analytical applications. Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
    Ribociclib (Standard)
  • HY-15777AS

    LEE011-d6 hydrochloride

    Isotope-Labeled Compounds CDK Cancer
    Ribociclib-d6 (LEE011-d6) hydrochloride is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
    Ribociclib-d6 hydrochloride
  • HY-15777AR

    LEE011 hydrochloride (Standard)

    Reference Standards CDK Cancer
    Ribociclib (Standard) (LEE011(Standard)) hydrochloride is the analytical standard of Ribociclib hydrochloride (HY-15777A). This product is intended for research and analytical applications. Ribociclib hydrochloride (LEE011 hydrochloride) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.
    Ribociclib hydrochloride (Standard)
  • HY-15777BR

    LEE011 succinate (Standard)

    CDK Reference Standards Cancer
    Ribociclib succinate (Standard) is the analytical standard of Ribociclib succinate. This product is intended for research and analytical applications. Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.
    Ribociclib succinate (Standard)
  • HY-15777S1

    LEE011-d8

    CDK Cancer
    Ribociclib-d8 is the deuterium labeled Ribociclib . Ribociclib (LEE01) is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex .
    Ribociclib-d8

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