1. Cell Cycle/DNA Damage
  2. CDK
  3. Ribociclib D6

Ribociclib D6 (Synonyms: LEE011 D6)

Cat. No.: HY-15777S
Handling Instructions

Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex.

For research use only. We do not sell to patients.

Ribociclib D6 Chemical Structure

Ribociclib D6 Chemical Structure

CAS No. : 1328934-40-2

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Description

Ribociclib D6 (LEE011 D6) is a deuterium labeled Ribociclib. Ribociclib is a highly specific CDK4/6 inhibitor with IC50 values of 10 nM and 39 nM, respectively, and is over 1,000-fold less potent against the cyclin B/CDK1 complex[1].

Molecular Weight

440.57

Formula

C₂₃H₂₄D₆N₈O

CAS No.

1328934-40-2

SMILES

O=C(C1=CC2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5)N(C([2H])([2H])[2H])C([2H])([2H])[2H]

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Ribociclib D6LEE011 D6Ribociclib D 6Ribociclib D-6CDKCyclin dependent kinaseInhibitorinhibitorinhibit

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