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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
Lipid Y
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "Lipid Y" in MCE Product Catalog:
Cat. No.: HY-126965
CAS No.: 88090-57-7
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Lipid Y is a potent monosaccharide which contains two bromines per chain. lipid Y binds to a tryptophan residue in a membrane protein and then quenches the fluorescence of the tryptophan residue .
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Synonyms: Magnogene, for insect cell culture, 97%
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Cat. No.: HY-130581
CAS No.: 86559-73-1
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Lipid X is a 2,3-diacylglucosamine-1-phosphate that serves as the monosaccharide precursor of lipid A, possessing both LPS antagonist and weak agonist activities. Lipid X exerts protective effects by inhibiting tumor necrosis factor production, monocyte procoagulant activity, and neutrophil priming. Lipid X may induce transient pulmonary hypertension, neutropenia, and mild pyrogenic effects in laboratory animals. Lipid X has low toxicity and no in vitro antibacterial activity, but it significantly reduces mortality following Gram-negative bacterial infection and endotoxin exposure. Lipid X tends to accumulate in liver tissue, binds to circulating cellular components, and can be converted to lipid Y through transesterification. Lipid X can be used in research on Gram-negative bacterial sepsis, endotoxemia, and associated pulmonary hypertension .
Cat. No.: HY-173234
CAS No.: 1008710-58-4
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GI-Y2 is an orally active, selective Gasdermin D (GSDMD) inhibitor (Kd = 36.0 μM) with anti-pyroptosis activity. GI-Y2 targets GSDMD, impairs membrane anchoring of GSDMD-NT, and blocks GSDMD‑dependent lipid binding and pore formation. GI-Y2 suppresses GSDMD‑dependent pyroptosis and inflammation, mitigates atherosclerosis and cardiac injury, boosts cell survival, and reduces IL‑1β/IL‑18 secretion. GI-Y2 can be used for the research of atherosclerosis and septic myocardial injury .
Cat. No.: HY-109506R
CAS No.: 63-89-8
Synonyms: 129Y83 (Standard)
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Ketones, Aldehydes, Acids Metabolic Disease Phenols Polyphenols Endogenous metabolite Disease Research Fields
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Cat. No.: HY-109506S10
Synonyms: 129Y83-13C
Cat. No.: HY-109506S2
CAS No.: 82765-17-1
Synonyms: (Rac)-129Y83-d6
Cat. No.: HY-W127442R
CAS No.: 2983-38-2
Synonyms: Ethyl 2-Ethylbutyrate (Standard)
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DPPC (Standard) is the analytical standard of DPPC. This product is intended for research and analytical applications. DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .
Cat. No.: HY-149596
CAS No.: 2231747-49-0
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PTZ-LD is a phenothiazine (HY-Y0055)-based fluorescent probe for lipid droplets (LDs) detection. PTZ-LD is apparently emissive in LDs with high specificity. (Ex/Em=488/570-620 nm). PTZ-LD can be used for diabetic cataract (DC) research .
Synonyms: Acetothioamide (Standard); TAA (Standard); Thiacetamide (Standard)
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Thioacetamide (Standard) is the analytical standard of Thioacetamide (HY-Y0698). This product is intended for research and analytical applications. Thioacetamide (TAA) is an indirect hepatotoxin and causes parenchymal cell necrosis. Thioacetamide requires metabolic activation by microsomal CYP2E1 to thioacetamide-S-oxide initially and then to thioacetamide-S-dioxide, which is a highly reactive metabolite, and its reactive metabolites covalently bind to proteins and lipids thereby causing oxidative stress and centrilobular necrosis. Thioacetamide can induce chronic liver fibrosis, encephalopathy and other events model .
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Cat. No.: HY-106849
CAS No.: 143375-60-4
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Y-26611 is an orally active new type of quinolone derivative. Y-26611 exhibits strong phototoxicity under UV irradiation and can significantly induce lipid peroxidation of human red blood cell membrane .
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Rhodamine B ethyl ester is a hydrophilic cationic derivative of Rhodamine B (HY-Y0016), belonging to non-selective cytotoxic agents and transporters. Rhodamine B ethyl ester exhibits broad-spectrum in vitro cytotoxicity and exerts cytotoxic effects on human tumor cells. Rhodamine B ethyl ester binds effectively to lipid membranes, undergoes voltage-dependent transport across planar bilayer phosphatidylcholine membranes, and its transport can be determined by current relaxation after voltage jump. Rhodamine B ethyl ester can be used in research related to cancers such as epithelioid melanoma and colorectal adenocarcinoma .
Cat. No.: HY-184409
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Antiparasitic agent-44 is an orally active Antiparasitic agent. Antiparasitic agent-44 reduces parasitemia levels, ROS, reactive nitrogen, lipid oxidation, protein oxidation, inflammatory responses and microstructural damage in Trypanosoma cruzi-infected mice. Antiparasitic agent-44 can be used for the research of Chagas disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
