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MBLAC2

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13322
    Pracinostat
    5+ Cited Publications

    SB939

    		 Beta-lactamase HDAC Apoptosis Cancer
    Pracinostat is a potent histone deacetylase (HDAC) inhibitor, with IC50s of 40-140 nM, used for cancer research. Pracinostat also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC50 below 10 nM .
    Pracinostat
  • HY-10990
    Abexinostat
    5 Publications Verification

    CRA 024781; PCI-24781

    		 HDAC Cancer
    Abexinostat (CRA 024781) is a novel pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM. Abexinostat also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC50 below 10 nM .
    Abexinostat
  • HY-100871
    WT-161
    5+ Cited Publications

    		 Beta-lactamase HDAC Apoptosis Cancer
    WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM . WT-161 also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) [2].
    WT-161
  • HY-13428
    Tubacin
    10+ Cited Publications

    		 Beta-lactamase HDAC Virus Protease Cancer
    Tubacin is a potent and selective inhibitor of HDAC6, with an IC50 value of 4 nM and approximately 350-fold selectivity over HDAC1. Tubacin also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2).
    Tubacin
  • HY-RS08189
    MBLAC2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others
    MBLAC2 Human Pre-designed siRNA Set A contains three designed siRNAs for MBLAC2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    MBLAC2 Human Pre-designed siRNA Set A
    MBLAC2 Human Pre-designed siRNA Set A
  • HY-19328
    ACY-775
    2 Publications Verification

    		 HDAC Cardiovascular Disease Neurological Disease
    ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5 nM [2]. ACY775 also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) .
    ACY-775
  • HY-13271
    Tubastatin A Hydrochloride
    Maximum Cited Publications
    23 Publications Verification

    Tubastatin A HCl; TSA HCl

    		 Beta-lactamase HDAC Autophagy Apoptosis Cancer
    Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).
    Tubastatin A Hydrochloride
  • HY-13271A
    Tubastatin A
    Maximum Cited Publications
    23 Publications Verification

    		 Beta-lactamase HDAC Autophagy Apoptosis Cancer
    Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).
    Tubastatin A
  • HY-13271B
    Tubastatin A TFA

    TSA TFA

    		 HDAC Autophagy Apoptosis Cancer
    Tubastatin A (TSA) TFA is a potent and selective?HDAC6?inhibitor with?IC50?of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A TFA also inhibits HDAC10 and metallo-β-lactamase domain-containing protein?2 (MBLAC2).
    Tubastatin A TFA

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