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Isoforms Recommended:	MGAT2

Results for "

MGAT2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (6) GABA Receptor (2) Small Interfering RNA (siRNA) (3)
By Research Areas:	Metabolic Disease (7) Neurological Disease (2)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

MGAT2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MGAT2 Human Pre-designed siRNA Set A contains three designed siRNAs for MGAT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MGAT2 Human Pre-designed siRNA Set A MGAT2 Human Pre-designed siRNA Set A

Mgat2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mgat2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mgat2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mgat2 Mouse Pre-designed siRNA Set A Mgat2 Mouse Pre-designed siRNA Set A

Mgat2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Mgat2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Mgat2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Mgat2 Rat Pre-designed siRNA Set A Mgat2 Rat Pre-designed siRNA Set A

MGAT2-IN-4	Others	Metabolic Disease
MGAT2-IN-4 (compound 33) is an inhibitor of monoacylglycerol transferase 2 (MGAT2), with liver metabolic stability. MGAT2-IN-4 can be used for research on obesity, diabetes and non-alcoholic steatohepatitis (NASH) .

MGAT2-IN-2	Acyltransferase	Metabolic Disease
MGAT2-IN-2 is a potent and selective acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) inhibitor with an IC₅₀ of 3.4 nM.

TP-020 MGAT2-IN-1	Acyltransferase	Metabolic Disease
TP-020 (MGAT2-IN-1) is an orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) with IC₅₀ of 7.8 and 2.4 nM for human and mouse MGAT2, respectively.

BMS-963272	Acyltransferase	Metabolic Disease
BMS-963272 is a potent, selective *MGAT2* inhibitor (IC₅₀ = 7.1 nM) for the research of metabolic disorders.

BMS-986172	Acyltransferase	Metabolic Disease
BMS-986172 is an orally active, highly selective *MGAT2* inhibitor with an IC₅₀ of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 has a T_1/2>120 min in vitro assays. BMS-986172 reduces food intake and body weight. BMS-986172 has the potential for metabolic disorders such as obesity and NASH research .

JTP-103237	Acyltransferase	Metabolic Disease
JTP-103237 is a *MGAT2* inhibitor (IC₅₀: 0.019 μM and 6.423 μM for hMGAT2 and hMGAT3 respectively). JTP-103237 modulates fat absorption, decreases plasma glucose levels and prevents diet-induced obesity .

NNC 05-2090 hydrochloride	GABA Receptor	Neurological Disease
NNC 05-2090 hydrochloride is a GABA uptake inhibitor and inhibitor of the β-GABA transporter (BGT-1) (IC_{50< /sub>}: 10.6 μM). NNC 05-2090 hydrochloride also inhibits *mGAT2* with a K_i value of 1.4 μM. NNC 05-2090 has anticonvulsant activity and can be used in the study of epilepsy and neurological diseases ^[2] .

NNC 05-2090	GABA Receptor	Neurological Disease
NNC 05-2090 is aGABA uptake inhibitor and inhibitor of the β-GABA transporter (BGT-1) (IC₅₀ sub>: 10.6 μM). NNC 05-2090 also inhibits *mGAT2* with a K_i value of 1.4 μM. NNC 05-2090 has anticonvulsant activity and can be used in the study of epilepsy and neurological diseases ^[2] .

T863 5+ Cited Publications	Acyltransferase	Metabolic Disease
T863 is an orally active, selective and potent DGAT1 (acyl-CoA:diacylglycerol acyltransferase 1) inhibitor with an IC₅₀ of 15 nM. T863 has no inhibitory activity against human MGAT3, human DGAT2, or human MGAT2. T863 interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells ^[2].

Cat. No.	Compare	Product Name	Species	Source

	MGAT2 Protein, Human (HEK293, His) rHuAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase/MGAT2, His ; Alpha-1; 6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase; Beta-1; 2-N-acetylglucosaminyltransferase II; GlcNAc-T II; NT-II; Mannoside Acetylglucosaminyltransferase 2; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II; MGAT2	Human	HEK293
	The MGAT2 protein plays an important role in protein N-glycosylation, catalyzing the transfer of GlcNAc to the free terminal mannose in nascent N-linked glycan chains. This forms a second branch of the complex glycan and is critical for glycoprotein maturation and functional diversity. MGAT2 Protein, Human (HEK293, His) is the recombinant human-derived MGAT2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MGAT2 Protein, Human (HEK293, His) is 418 a.a., with molecular weight of ~50.0 kDa.


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