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N-(4-acetamidophenyl)-Indomethacin amide

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Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-135081
    N-(4-acetamidophenyl)-Indomethacin amide

    N-4AIA

    		 COX Others
    N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.1 N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 μM, respectively. It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.
    N-(4-acetamidophenyl)-Indomethacin amide

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