N-(4-acetamidophenyl)-Indomethacin amide

(Synonyms: N-4AIA)

N-(4-acetamidophenyl)-indomethacin amide (N-4-AIA) is one of several aromatic amides of indomethacin reported to be potent and selective reversible inhibitors of COX-2.1 N-4-AIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 μM, respectively. It is about 400 times less potent as an inhibitor of human recombinant COX-1 and 80 times less potent as an inhibitor of ovine COX-1 than ovine COX-2.

For research use only. We do not sell to patients.

  • CAS No.: 261766-23-8
  • Formula: C27H24ClN3O4
  • Molecular Weight:489.95
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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