1. Cytoskeleton
  2. Gap Junction Protein
  3. Meclofenamic acid sodium

Meclofenamic acid sodium (Synonyms: Meclofenamate sodium)

Cat. No.: HY-B1320 Purity: 99.86%
Handling Instructions

Meclofenamic acid (Meclofenamate) sodium is a nonsteroidal anti-inflammatory drug (NSAID) approved for use in arthritis (osteo and rheumatoid), analgesia (mild to moderate pain), dysmenorrhea, and heavy menstrual blood loss (menorrhagia). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor.

For research use only. We do not sell to patients.

Meclofenamic acid sodium Chemical Structure

Meclofenamic acid sodium Chemical Structure

CAS No. : 6385-02-0

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
50 mg USD 50 In-stock
Estimated Time of Arrival: December 31
100 mg USD 90 In-stock
Estimated Time of Arrival: December 31
200 mg USD 150 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

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Customer Review

Based on 4 publication(s) in Google Scholar

Other Forms of Meclofenamic acid sodium:

Top Publications Citing Use of Products

    Meclofenamic acid sodium purchased from MCE. Usage Cited in: Theranostics. 2021 Jul 25;11(17):8464-8479.

    The effect of FTO inhibitor Meclofenamate sodium (MS) (80 μM and 120 μM) on ATF4 protein expression and mTORC1 activity during 968 treatment is detected by western blotting. MS efficiently reduces ATF4 expression and rescues the mTOR downregulation induced by compound 968.
    • Biological Activity

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    • Customer Review

    Description

    Meclofenamic acid (Meclofenamate) sodium is a nonsteroidal anti-inflammatory drug (NSAID) approved for use in arthritis (osteo and rheumatoid), analgesia (mild to moderate pain), dysmenorrhea, and heavy menstrual blood loss (menorrhagia). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor[1][2][3].

    Clinical Trial
    Molecular Weight

    318.13

    Formula

    C₁₄H₁₀Cl₂NNaO₂

    CAS No.
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    4°C, protect from light

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

    Solvent & Solubility
    In Vitro: 

    DMSO : 125 mg/mL (392.92 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.1434 mL 15.7168 mL 31.4337 mL
    5 mM 0.6287 mL 3.1434 mL 6.2867 mL
    10 mM 0.3143 mL 1.5717 mL 3.1434 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

      Solubility: ≥ 2.08 mg/mL (6.54 mM); Clear solution

    • 2.

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

      Solubility: ≥ 2.08 mg/mL (6.54 mM); Clear solution

    • 3.

      Add each solvent one by one:  10% DMSO    90% corn oil

      Solubility: ≥ 2.08 mg/mL (6.54 mM); Clear solution

    *All of the co-solvents are provided by MCE.
    References

    Purity: 99.86%

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    Product Name:
    Meclofenamic acid sodium
    Cat. No.:
    HY-B1320
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