1. Metabolic Enzyme/Protease
    Apoptosis
  2. Fatty Acid Synthase (FAS)
    Apoptosis
  3. Orlistat

Orlistat (Synonyms: Tetrahydrolipstatin; Ro-18-0647)

Cat. No.: HY-B0218 Purity: 99.75%
Handling Instructions

Orlistat is a lipase inhibitor for obesity management that acts by inhibiting the absorption of dietary fats.

For research use only. We do not sell to patients.

Orlistat Chemical Structure

Orlistat Chemical Structure

CAS No. : 96829-58-2

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
200 mg USD 94 In-stock
Estimated Time of Arrival: December 31
500 mg USD 208 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 3 publication(s) in Google Scholar

Top Publications Citing Use of Products

    Orlistat purchased from MCE. Usage Cited in: Nutrients. 2018 Mar 15;10(3). pii: E353.

    Treatment with Orlistat leads to increased phospho-ACC without affecting the phosphorylation status of TOPK/survivin.
    • Biological Activity

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    • References

    • Customer Review

    Description

    Orlistat is a lipase inhibitor for obesity management that acts by inhibiting the absorption of dietary fats.

    Clinical Trial
    Molecular Weight

    495.73

    Formula

    C₂₉H₅₃NO₅

    CAS No.

    96829-58-2

    SMILES

    O=C1[[email protected]@H](CCCCCC)[[email protected]](C[[email protected]@H](OC([[email protected]@H](N([H])C([H])=O)CC(C)C)=O)CCCCCCCCCCC)O1

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Solvent & Solubility
    In Vitro: 

    DMSO : ≥ 100 mg/mL (201.72 mM)

    H2O : < 0.1 mg/mL (insoluble)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.0172 mL 10.0861 mL 20.1723 mL
    5 mM 0.4034 mL 2.0172 mL 4.0345 mL
    10 mM 0.2017 mL 1.0086 mL 2.0172 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

      Solubility: ≥ 2.5 mg/mL (5.04 mM); Clear solution

    • 2.

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

      Solubility: 2.5 mg/mL (5.04 mM); Suspended solution; Need ultrasonic

    • 3.

      Add each solvent one by one:  10% DMSO    90% corn oil

      Solubility: ≥ 2.5 mg/mL (5.04 mM); Clear solution

    *All of the co-solvents are provided by MCE.
    References
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    • Molarity Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    × = ×
    C1   V1   C2   V2

    Keywords:

    OrlistatTetrahydrolipstatinRo-18-0647Fatty Acid Synthase (FAS)ApoptosisInhibitorinhibitorinhibit

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    Product name:
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    Cat. No.:
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