6385-02-0
6385-02-0
Chemical Structure
Meclofenamic acid sodium
Synonym(s): Meclofenamate sodium
- CAS No.: 6385-02-0
- Formula:C14H10Cl2NNaO2
- Molecular Weight:318.13
IUPAC Name: sodium 2-((2,6-dichloro-3-methylphenyl)amino)benzoate
InChIKey: OGPIIGMUPMPMNT-UHFFFAOYSA-M
SMILES: O=C(O[Na])C1=CC=CC=C1NC2=C(Cl)C=CC(C)=C2Cl
Biological Activity: Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities[1][2][3].
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Meclofenamic acid sodium | 99.89% | Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities. | ||||||||||||||||||||
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Meclofenamic acid sodium (Standard) | ≥98% | Meclofenamic acid (sodium) (Standard) is the analytical standard of Meclofenamic acid (sodium). This product is intended for research and analytical applications. Meclofenamic acid (Meclofenamate) sodium is a non-steroidal anti-inflammatory agent (NSAID). Meclofenamic acid sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat - and obesity-related enzyme (FTO). Meclofenamic acid sodium has anti-inflammatory and antitumor activities. | ||||||||||||||||||||
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References
- [1]. Schober W, et al. Meclofenamic acid for inhibition of human vascular smooth muscle cell proliferation and migration: an in vitro study. Cardiovasc Intervent Radiol. 2002 Jan-Feb;25(1):57-63. [Content Brief]
- [2]. Chen H, et al. Meclofenamic Acid Restores Gefinitib Sensitivity by Downregulating Breast Cancer Resistance Protein and Multidrug Resistance Protein 7 via FTO/m6A-Demethylation/c-Myc in Non-Small Cell Lung Cancer. Front Oncol. 2022 Apr 21;12:870636. [Content Brief]
- [3]. Schrier DJ, et al. The topical anti-inflammatory effects of a topical preparation of meclofenamic acid on carrageenan-induced footpad swelling in mice. J Pharm Pharmacol. 1987 Jan;39(1):57-9. [Content Brief]
