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Results for "

OSMR

" in MedChemExpress (MCE) Product Catalog:

1

Inhibitors & Agonists

4

Recombinant Proteins

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Cat. No. Compare Product Name Species Source
  • HY-P72500
    OSMR beta Protein, Human (712a.a, HEK293, His)

    Oncostatin-M-specific receptor subunit beta; IL-31R-beta; IL-31RB; OSMR; OSMRB

    		Human HEK293
    The OSMR beta protein is critical in immune responses by binding to IL12RB1 to form the interleukin 23 receptor with IL-23R. It binds to IL23 and activates T cells, NK cells and potentially macrophages/myeloid cells through Jak-Stat signaling. OSMR beta Protein, Human (712a.a, HEK293, His) is the recombinant human-derived OSMR beta protein, expressed by HEK293 , with C-6*His labeled tag. The total length of OSMR beta Protein, Human (712a.a, HEK293, His) is 712 a.a., with molecular weight of ~132 kDa.
  • HY-P78333
    OSMR beta Protein, Mouse (HEK293, His)

    IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ; IL-31R subunit β; IL-31R-β; OSMR β

    		 Mouse HEK293
    The OSMR beta Protein, in partnership with IL31RA, constitutes the IL31 receptor, binding IL31 to activate STAT3, and potentially STAT1 and STAT5. OSMR beta also transduces OSM-specific signaling. It forms a heterodimer with IL6ST, creating the type II OSM receptor, and another heterodimer with IL31RA for the IL31 receptor. OSMR beta Protein, Mouse (HEK293, His) is the recombinant mouse-derived OSMR beta protein, expressed by HEK293, with C-His labeled tag. The total length of OSMR beta Protein, Mouse (HEK293, His) is 714 a.a., with molecular weight of 115-140 kDa.
  • HY-P700806
    OSMR beta Protein, Cynomolgus (HEK293, His)

    IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ; IL-31R subunit β; IL-31R-β; OSMR β

    		 Cynomolgus HEK293
    OSMR beta Protein, a type I cytokine receptor in the type 2 subfamily, is pivotal in cellular signaling and immune responses. Serving as the receptor for oncostatin M, a cytokine with roles in inflammation, cell growth, and differentiation, OSMR beta is crucial for downstream signaling and cellular function regulation. Exploring OSMR beta's function and regulation offers insights for developing therapeutic strategies addressing diseases associated with cytokine signaling or immune response dysregulation. OSMR beta Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived OSMR beta protein, expressed by HEK293, with C-His labeled tag. The total length of OSMR beta Protein, Cynomolgus (HEK293, His) is 710 a.a., with molecular weight of 110-130 kDa.
  • HY-P700807
    OSMR&GP130 Protein, Human (HEK293, His-Flag)

    		Human HEK293
    OSMR beta Protein, crucial in immune response, forms the interleukin-23 receptor with IL-23R by associating with IL12RB1. Binding IL23, it activates T-cells, NK cells, and potentially macrophage/myeloid cells through Jak-Stat signaling. Involved in innate and adaptive immunity, IL23 contributes to acute infection response and is implicated in autoimmune diseases and tumorigenesis. In the presence of IL12RB1, OSMR beta forms a heterodimeric IL-23 receptor, interacting with JAK2 and activating STAT3. OSMR&GP130 Protein, Human (HEK293, His-Flag) is a recombinant protein dimer complex containing human-derived OSMR&GP130 protein, expressed by HEK293, with C-His, C-Flag labeled tag. OSMR&GP130 Protein, Human (HEK293, His-Flag), has molecular weight of 100-140 kDa.

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