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  5. OSMR beta Protein, Cynomolgus (HEK293, His)

OSMR beta Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P700806
Handling Instructions

OSMR beta Protein, a type I cytokine receptor in the type 2 subfamily, is pivotal in cellular signaling and immune responses. Serving as the receptor for oncostatin M, a cytokine with roles in inflammation, cell growth, and differentiation, OSMR beta is crucial for downstream signaling and cellular function regulation. Exploring OSMR beta's function and regulation offers insights for developing therapeutic strategies addressing diseases associated with cytokine signaling or immune response dysregulation. OSMR beta Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived OSMR beta protein, expressed by HEK293, with C-His labeled tag. The total length of OSMR beta Protein, Cynomolgus (HEK293, His) is 710 a.a., with molecular weight of 110-130 kDa.

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Description

OSMR beta Protein, a type I cytokine receptor in the type 2 subfamily, is pivotal in cellular signaling and immune responses. Serving as the receptor for oncostatin M, a cytokine with roles in inflammation, cell growth, and differentiation, OSMR beta is crucial for downstream signaling and cellular function regulation. Exploring OSMR beta's function and regulation offers insights for developing therapeutic strategies addressing diseases associated with cytokine signaling or immune response dysregulation. OSMR beta Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived OSMR beta protein, expressed by HEK293, with C-His labeled tag. The total length of OSMR beta Protein, Cynomolgus (HEK293, His) is 710 a.a., with molecular weight of 110-130 kDa.

Background

The OSMR beta protein belongs to the type I cytokine receptor family, specifically the type 2 subfamily. This protein plays a significant role in cellular signaling and immune responses. It acts as a receptor for oncostatin M, a cytokine involved in various biological processes such as inflammation, cell growth, and differentiation. The OSMR beta protein is essential for the activation of downstream signaling pathways and the regulation of cellular functions. Understanding the function and regulation of OSMR beta protein can provide valuable insights into the development of therapeutic strategies for diseases involving dysregulation of cytokine signaling or immune responses.

Species

Cynomolgus

Source

HEK293

Tag

C-His

Accession

A0A2K5UFW5 (E28-S737)

Gene ID

102135082

Molecular Construction
N-term
OSMR beta (E28-S737)
Accession # A0A2K5UFW5
His
C-term
Synonyms
IL-31R subunit beta; IL-31R-beta; IL-31RB; OSMR beta; OSMR; OSMRB; OSMRBMGC150626; PLCA1 ; IL-31R subunit β; IL-31R-β; OSMR β
Molecular Weight

110-130 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

OSMR beta Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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OSMR beta Protein, Cynomolgus (HEK293, His)
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HY-P700806
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