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Results for "

TGN

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Inhibitory Antibodies

1

Recombinant Proteins

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W008574
    TGN-020
    5+ Cited Publications

    		 PROTAC Linkers Inflammation/Immunology Cancer
    TGN-020 is a selective Aquaporin 4 (AQP4) inhibitor with an IC50 of 3.1 μM . TGN-020 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs [3].TGN-020 alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .
    <em>TGN</em>-020
  • HY-W008574A
    TGN-020 sodium
    5+ Cited Publications

    		 PROTAC Linkers Inflammation/Immunology Cancer
    TGN-020 sodium is a selective Aquaporin 4 (AQP4) inhibitor with an IC50 of 3.1 μM . TGN-020 sodium is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . TGN-020 sodium alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .
    <em>TGN</em>-020 sodium
  • HY-P9975
    Theralizumab

    TGN1412

    		 CD28 Inflammation/Immunology
    Theralizumab (TGN1412) is a humanized lgG4 superagonistic anti-CD28 monoclonal antibody that directly stimulates T cells. Theralizumab can cause cytokine release syndrome (CRS). Theralizumab can be used for the research of rheumatoid arthritis .
    Theralizumab
  • HY-137975
    Exo2

    		Others Endocrinology
    Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells .
    Exo2
  • HY-10270
    Flovagatran

    TGN 255

    		 Thrombin Cardiovascular Disease
    Flovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM). Flovagatran can be used in the research of arterial and venous thrombosis .
    Flovagatran

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