2. Metabolic Enzyme/Protease
  3. Thrombin
  4. Flovagatran

Flovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM). Flovagatran can be used in the research of arterial and venous thrombosis.

For research use only. We do not sell to patients.

Flovagatran Chemical Structure

Flovagatran Chemical Structure

CAS No. : 871576-03-3

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Flovagatran Related Antibodies

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Description

Flovagatran (TGN 255) is a potent and reversible thrombin inhibitor (Ki: 9 nM). Flovagatran can be used in the research of arterial and venous thrombosis[1].

In Vivo

Flovagatran (2.5-mg/kg bolus plus 10 mg/kg/h for 90 minutes) produces anticoagulation effects in dogs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Chicks[1]
Dosage: 1.0-mg/kg bolus and then 4 mg/kg/h for 90 minutes.
2.5-mg/kg bolus and then 10 mg/kg/h for 90 minutes.
5.0-mg/kg bolus and then 20 mg/kg/h for 90 minutes.
Administration: Bolus plus infusion
Result: Elevated PD markers, and produced minimal post-operative blood loss.
Molecular Weight

525.40

Formula

C27H36BN3O7
CAS No.
SMILES

O=C(OCC1=CC=CC=C1)N[C@H](CC2=CC=CC=C2)C(N3CCC[C@H]3C(N[C@@H](CCCOC)B(O)O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Flovagatran Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Flovagatran871576-03-3TGN 255TGN255TGN-255ThrombinThrombosisanticoagulationInhibitorinhibitorinhibit

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