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Results for "

TRPA1-IN-4

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18662
    RQ-00203078
    5+ Cited Publications

    		 TRP Channel Neurological Disease Cancer
    RQ-00203078 is a highly selective, potent and orally active TRPM8 antagonist with IC50s of 5.3 nM and 8.3 nM for rat and human TRPM8 channels, respectively. RQ-00203078 shows little inhibitory action against TRPV1, TRPA1, TRPV4, or TRPM2 channels .
    RQ-00203078
  • HY-172898
    TRPA1-IN-4

    		TRP Channel Neurological Disease
    TRPA1-IN-4 (12) is a TRPA1 inhibitor, with an IC50 of 45 nM. TRPA1-IN-4 (12) can be used in the pain research .
    TRPA1-IN-4
  • HY-178236
    TRPM5 agonist-1

    		TRP Channel Metabolic Disease
    TRPM5 agonist-1 is an orally active TRPM5 agonist with a pEC50 of 8.1. TRPM5 agonist-1 shows excellent selectivity (> 100-fold) versus related cation channels (TRPM8, TRPV1, TRPV4, TRPA1, TRPM4). TRPM5 agonist-1 exhibits locally acting stimulatory effect on gastrointestinal transit in mice. TRPM5 agonist-1 can be used for research on promoting gastric motility .
    TRPM5 agonist-1
  • HY-122692
    TRPV4/TRPA1-IN-1

    		TRP Channel Neurological Disease Inflammation/Immunology
    TRPV4/TRPA1-IN-1 is a TRPV4/TRPA1 inhibitor that suppresses TRPV4/TRPA1-mediated calcium influx. TRPV4/TRPA1-IN-1 alleviates pain behaviors in a mouse trigeminal stimulation pain model and inhibits inflammation and pain-related behaviors in a mouse acute pancreatitis model. TRPV4/TRPA1-IN-1 can be used in research on acute pancreatitis .
    TRPV4/TRPA1-IN-1

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