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Pathways Recommended: Stem Cell/Wnt Cell Cycle/DNA Damage
Results for "

U118 glioblastoma cells

" in MedChemExpress (MCE) Product Catalog:

4

阻害剤およびアゴニスト

1

阻害性抗体

Targets Recommended:
製品番号 製品名 Target 研究分野 構造式
  • HY-P99223
    Tovetumab

    MEDI-575

    		 PDGFR Cancer
    Tovetumab (MEDI-575) is an anti-PDGFRα monoclonal antibody that selectively blocks the PDGFRα signal transduction. Tovetumab can be used in the research of glioblastoma and non-small cell lung cancer (NSCLC) .
    Tovetumab
  • HY-178969
    GZD-257

    		FAK Pyk2 Apoptosis Neurological Disease Cancer
    GZD-257 is a brain-penetrant, ATP-competitive FAK inhibitor (IC50 = 14.3 nM), performing 4.77-fold selectivity with FAK to Pyk2 (IC50 = 68.2 nM). GZD-257 can significantly induce apoptosis of U118MG cells and arrest the cell cycle at the G2/M phase. GZD-257 can be used for the study of Glioblastoma (GBM) .
    GZD-257
  • HY-183638
    T7117

    		E1/E2/E3 Enzyme HIF/HIF Prolyl-Hydroxylase Neurological Disease Cancer
    T7117 is a TRIM25-HIF-1α inhibitor. T7117 disrupts the interaction between TRIM25-HIF-1α. T7117 can be used for the research of glioblastoma .
    T7117
  • HY-170778
    Tubulin polymerization-IN-77

    		Microtubule/Tubulin Cancer
    Tubulin polymerization-IN-77 (Compound 15c) is a tubulin polymerization inhibitor that exerts anti-glioblastoma activity by inhibiting tubulin polymerization. Tubulin polymerization-IN-77 demonstrates significant blood-brain barrier permeability, effectively inducing G2/M phase arrest and triggering apoptosis in GBM cells, while also significantly inhibiting tumor cell migration .
    Tubulin polymerization-IN-77

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