2. Search Result
Search Result
Results for "

Wee1+kinase

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-175749
    BMS-986463

    		Molecular Glues Wee1 Inflammation/Immunology Cancer
    BMS-986463, a CRBN E3 ligase modulator (CELMoD), is a WEE1 kinase molecular glue degrader. BMS-986463 significantly inhibits tumor regression and reduces the level of phospho-CDK2. BMS-986463 can be used for advanced malignant solid tumors like non-small cell lung cancer (NSCLC) research [1].
    BMS-986463
  • HY-138239
    WEE1-IN-3

    		Wee1 Cancer
    WEE1-IN-3 is a potent Wee1 kinase inhibitor with an IC50 of <10 nM. WEE1-IN-3 has anticancer activities [1].
    WEE1-IN-3
  • HY-108343
    WEE1-IN-4
    1 Publications Verification

    		 Wee1 Cancer
    WEE1-IN-4 (compound 15) is a pyrrolocarbazole-1,3(2H,6H)-dione derivative and Wee1 kinase inhibitor with an IC50 value of 11 nM.WEE1-IN-4 can be used for the research of cancer [1].
    WEE1-IN-4
  • HY-161880
    WEE1-IN-10

    		Wee1 Cancer
    WEE1-IN-10 (compound 77) is a Wee1 kinase inhibitor. WEE1-IN-10 shows inhibitory activity on LOVO cell growth, with an IC50 of 0.524 μM. WEE1-IN-10 can be used for the research of diseases caused by abnormal activity of Wee1 [1].
    WEE1-IN-10
  • HY-178190
    WEE1-IN-13

    		Wee1 Cancer
    WEE1-IN-13 (Compound 10) is a highly selective WEE1 kinase inhibitor (IC50=0.7 nM). WEE1-IN-13 abrogates the G2/M checkpoint and induces tumor cell apoptosis. WEE1-IN-13 is promising for research of solid tumors (e.g., non-small cell lung cancer, ovarian cancer) [1].
    WEE1-IN-13
  • HY-174448
    WEE1-IN-12

    		Wee1 Cancer
    WEE1-IN-12 (Compound 87) is a Wee1 kinase inhibitor with an IC50 of 2.0 nM. WEE1-IN-12 can inhibit the proliferation of HT29 cells (IC50: 1.07 μM), and when used in combination with Gemcitabine (HY-17026), the effect is better (IC50: 0.34 μM). WEE1-IN-12 can be used in the research of tumors such as colon cancer [1].
    WEE1-IN-12
  • HY-182433
    CJM061

    		Wee1 Neurological Disease Cancer
    CJM061 is a WEE1 kinase inhibitor with a target IC50 of 2.8 nM. CJM061 acts as a sensitizer and exhibits synergistic effects with Cisplatin (HY-17394) in medulloblastoma cells. CJM061 can be used for the research of medulloblastoma [1].
    CJM061
  • HY-183278
    APO-50815

    		Wee1 Apoptosis Cancer
    APO-50815 is a WEE1 kinase inhibitor with a human IC50 of 9 nM. APO-50815 induces DNA damage, replication stress, S-phase cell accumulation, and apoptosis. APO-50815 can be used for the research of metastatic colorectal cancer [1].
    APO-50815
  • HY-108343R
    WEE1-IN-4 (Standard)

    		Reference Standards Wee1 Cancer
    WEE1-IN-4 (Standard) is the analytical standard of WEE1-IN-4 (HY-108343). This product is intended for research and analytical applications. WEE1-IN-4 (Compound 15) is a potent checkpoint Wee1 Kinase inhibitor with an IC50 of 0.011 μM. Wee1 inhibitors can abrogate the G2/M checkpoint [1].
    WEE1-IN-4 (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: