WEE1-IN-10
WEE1-IN-10 (compound 77) is a Wee1 kinase inhibitor. WEE1-IN-10 shows inhibitory activity on LOVO cell growth, with an IC50 of 0.524 μM. WEE1-IN-10 can be used for the research of diseases caused by abnormal activity of Wee1.
For research use only. We do not sell to patients.
- CAS No.: 2226938-19-6
- Formula: C28H30Cl2N8O
- Molecular Weight:565.50
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2226938-19-6
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Appearance Solid
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Molecular Weight 565.50
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Formula C28H30Cl2N8O
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Color light yellow
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SMILES
CC1=C(N2C[C@H](C)N(C)[C@H](C)C2)C=CC(NC3=NC=C4C(N5C(N(C6=C(Cl)C=CC=C6Cl)C4=O)=NCC5)=N3)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (88.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7683 mL | 8.8417 mL | 17.6835 mL | 44.2087 mL |
| 5 mM | 0.3537 mL | 1.7683 mL | 3.5367 mL | 8.8417 mL | |
| 10 mM | 0.1768 mL | 0.8842 mL | 1.7683 mL | 4.4209 mL | |
| 15 mM | 0.1179 mL | 0.5894 mL | 1.1789 mL | 2.9472 mL | |
| 20 mM | 0.0884 mL | 0.4421 mL | 0.8842 mL | 2.2104 mL | |
| 25 mM | 0.0707 mL | 0.3537 mL | 0.7073 mL | 1.7683 mL | |
| 30 mM | 0.0589 mL | 0.2947 mL | 0.5894 mL | 1.4736 mL | |
| 40 mM | 0.0442 mL | 0.2210 mL | 0.4421 mL | 1.1052 mL | |
| 50 mM | 0.0354 mL | 0.1768 mL | 0.3537 mL | 0.8842 mL | |
| 60 mM | 0.0295 mL | 0.1474 mL | 0.2947 mL | 0.7368 mL | |
| 80 mM | 0.0221 mL | 0.1105 mL | 0.2210 mL | 0.5526 mL |
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