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Results for "

XP

" in MedChemExpress (MCE) Product Catalog:

8

Inhibitors & Agonists

1

Peptides

1

Natural
Products

1

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-147008
    XP-524

    		Epigenetic Reader Domain Cancer
    XP-524 is a potent BET and EP300 inhibitor. XP-524 shows great tumoricidal activity in vivo. XP-524 prevents KRAS-induced, neoplastic transformation in vivo and extends survival in two transgenic mouse models of aggressive PDAC. XP-524 also enhances the presentation of self-peptide and tumor recruitment of cytotoxic T lymphocytes. XP-524 has the potential for the research of pancreatic ductal adenocarcinoma (PDAC) .
    <em>XP</em>-524
  • HY-136284
    XP-59
    1 Publications Verification

    		 SARS-CoV Infection
    XP-59 is a potent inhibitor of the SARS-CoV M pro, with a Ki of 0.1 μM .
    <em>XP</em>-59
  • HY-16216
    Gabapentin enacarbil

    XP-13512

    		 Calcium Channel Neurological Disease
    Gabapentin enacarbil (XP-13512) is a prodrug for the anticonvulsant and analgesic drug gabapentin.
    Gabapentin enacarbil
  • HY-139994
    XN methyl pyrazole

    XP

    		 Others Metabolic Disease Cancer
    XN methyl pyrazole improves diet-induced obesity and induces energy expenditure in high-fat diet-fed mice .
    XN methyl pyrazole
  • HY-115885
    XP5

    		HDAC Inflammation/Immunology Cancer
    XP5 is a potent, orally active HDAC6 inhibitor with an IC50 of 31 nM. XP5 displays high antiproliferative activity against various cancer cell lines including the HDACi-resistant YCC3/7 gastric cancer cells (IC50=0.16-2.31 μM). XP5 enhances antitumor immunity when combined with a PD-L1 inhibitor in melanoma .
    <em>XP</em>5
  • HY-109105
    Tepilamide fumarate

    XP-23829; PPC-06

    		 Others Inflammation/Immunology
    Tepilamide fumarate (XP-23829; PPC-06) is an oral fumaric acid ester, acts as a proagent of Monomethyl fumarate (HY-103252), and is used in the research of moderate to severe chronic plaque psoriasis .
    Tepilamide fumarate
  • HY-14735
    Arbaclofen placarbil

    XP 19986

    		 GABA Receptor Neurological Disease
    Arbaclofen placarbil is a novel transported proagent of the active R-isomer of baclofen. Baclofen is a racemic GABAB receptor agonist
    Arbaclofen placarbil
  • HY-N0381
    Maackiain

    DL-​Maackiain

    		 Parasite Apoptosis Infection
    Maackiain (DL-Maackiain) is isolated from Maackia amurensis Rupr.et Maxim. Maackiain (DL-Maackiain) is a larvicidal agent against Aedes aegypti mosquito.xp Parasitol with a LD50 of  21.95 µg/mL . Maackiain (DL-Maackiain) induces fragmentations of DNA to oligonucleosomal-sized fragments that like a characteristic of apoptosis in the HL-60 cells .
    Maackiain

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