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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
amidation reactions
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "amidation reactions" in MCE Product Catalog:
14
14 Cited Publications
Cat. No.: HY-D0178
CAS No.: 25952-53-8
1
1 Cited Publications
Cat. No.: HY-30014
CAS No.: 348640-06-2
Cat. No.: HY-69142
CAS No.: 374068-01-6
Target:
Research Areas:
2-Chloropyrimidine-5-carboxylic acid is a synthetic intermediate of Vanin-1 inhibitor 2 .
Synonyms: 5-Azidovaleric acid
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Research Areas:
5-Azidopentanoic acid (5-Azidovaleric acid) is a crosslinker/cyclization reagent as well as an azido-containing carboxylic acid. 5-Azidopentanoic acid participates in Cu I-catalyzed azide-alkyne cycloaddition reactions; when used to cap the N-terminus of resin-bound peptides containing propargylglycine residues, it enables head-to-tail cyclodimerization of peptides. 5-Azidopentanoic acid introduces azido functional groups into chitosan via amidation for strain-promoted azide-alkyne cycloaddition click reactions. 5-Azidopentanoic acid acts as an aliphatic bifunctional ligand and capping agent for CdSe tetrapods; its bromo group can be converted to an azido group, which then undergoes catalyst-free alkyne-azide cycloaddition click reactions with ethynyl-terminated poly (3-hexylthiophene) .
Cat. No.: HY-30156
CAS No.: 10592-27-5
Synonyms: 7-Azaindoline
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Research Areas:
2,3-Dihydro-7-azaindole (7-Azaindoline) is a cyclic secondary amine substrate with a fused aromatic ring, which serves as a substrate for hydrogenation reactions. 2,3-Dihydro-7-azaindole undergoes amidation with methyl pyrazine-2-carboxylate under the catalysis of lipase from Pseudomonas stutzeri. 2,3-Dihydro-7-azaindole is often used as an intermediate in organic synthesis, for example, in the preparation of indole compounds .
Cat. No.: HY-W127342
CAS No.: 112-13-0
Synonyms: Decanoic acid chloride
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Decanoyl chloride is an organic compound belonging to the class of acid chlorides. It is a colorless liquid with a pungent odor and is commonly used as a reagent in various organic chemical reactions, especially in the synthesis of esters, amides and fatty acids. Decanoyl chloride has numerous applications in synthetic organic chemistry, especially in the production of pharmaceuticals, agrochemicals and specialty chemicals. In addition, it can be used as a precursor for the synthesis of surfactants and detergents.
Cat. No.: HY-W010361
CAS No.: 10581-12-1
Cat. No.: HY-W800837
CAS No.: 2231240-82-5
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t-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit dipeptide is cleavable by cell proteases and features a carboxylic acid which is free for coupling reactions with amines to form amides. The Boc can be removed under acidic conditions to reveal a free primary amine, which may be used in a variety of reactions such as coupling or reductive amination.
Cat. No.: HY-W800621
CAS No.: 2055024-59-2
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Fmoc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine for use in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
Cat. No.: HY-W800622
CAS No.: 2055024-58-1
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Research Areas:
Fmoc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
Cat. No.: HY-W800623
CAS No.: 2055024-57-0
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Research Areas:
Fmoc-PEG6-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Fmoc protecting group may be removed with piperidine to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
Cat. No.: HY-W800624
CAS No.: 2055024-55-8
Target:
Research Areas:
Boc-PEG2-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Boc protecting group may be removed with acid to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
Cat. No.: HY-W800625
CAS No.: 2055024-54-7
Target:
Research Areas:
Boc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzylic alcohol on the PAB can be used to attach with reactive groups such as PNP for conjugation with drug payloads. The Boc protecting group may be removed with acid to reveal a primary amine which may be used in coupling reactions to form amides. The Val-Cit-PAB is cleaved by cellular proteases for efficient release of payloads to the cell.
Cat. No.: HY-E70997
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Research Areas:
Glycopeptidase A, Almonds (EC 3.5.1.52) is an enzyme that catalyzes a chemical reaction that cleaves a N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. Glycopeptidase A, Almonds (EC 3.5.1.52) belongs to the family of hydrolases, specifically those acting on carbon-nitrogen bonds other than peptide bonds in linear amides.
Cat. No.: HY-183002
CAS No.: 2451420-52-1
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N6-(3-Azidopropanoyl)-N2-(tert-butoxycarbonyl)-L-lysine is an L-lysine (HY-N0469) derivative and an azide molecule used for click chemistry conjugation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
