t-Boc-N-amido-PEG4-Val-Cit
t-Boc-N-amido-PEG4-Val-Cit is a protease-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit dipeptide. The Val-Cit dipeptide is cleavable by cell proteases and features a carboxylic acid which is free for coupling reactions with amines to form amides. The Boc can be removed under acidic conditions to reveal a free primary amine, which may be used in a variety of reactions such as coupling or reductive amination.
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- CAS No.: 2231240-82-5
- Formula: C27H51N5O11
- Molecular Weight:621.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2231240-82-5
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Molecular Weight 621.72
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Formula C27H51N5O11
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SMILES
NC(NCCC[C@@H](C(O)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(OC(C)(C)C)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
t-Boc-N-amido-PEG4-Val-Cit Related Classifications
HY-W800837 Related Classifications
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