2. Search Result
Search Result
Results for "

anxiety-related disorders

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103505
    CL 218872

    		GABA Receptor Neurological Disease
    CL 218872 is an orally active and selective ligand for the benzodiazepine receptor subtype BZ1. CL 218872 exhibits anxiolytic, sedative and anticonvulsant activities. CL 218872 can be used in researches of anxiety related disorders and epilepsy .
    CL 218872
  • HY-101834
    ACT-462206

    		Orexin Receptor (OX Receptor) Others
    ACT-462206 is an orally active and potent dual Orexin 1/Orexin 2 receptor antagonist with IC50s of 60 nM (Orexin 1) and 11 nM (Orexin 2), respectively. ACT-462206 exhibits brain penetration properties, and can be used for insomnia, stress/anxiety-related disorders and addiction research .
    ACT-462206
  • HY-128174
    β-CCM

    Beta-CCM; Ro 22-7497

    		 GABA Receptor Neurological Disease
    β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and proconvulsant effects. β-CCM enhances emotional reactivity and reduces vulnerability to interference in spatial working memory tasks. β-CCM can be used for research on anxiety-related disorders .
    β-CCM
  • HY-W794785
    WAY 208466

    		5-HT Receptor Neurological Disease
    WAY 208466 is a selective 5-HT6 receptor agonist with an EC50 of 7.3 nM. WAY-208466 increases GABA levels following both acute and chronic administration in the dorsolateral frontal cortex of rat models with stereotaxic surgery. WAY 208466 can be used for anxiety-related disorders like obsessive compulsive disorder (OCD) research .
    WAY 208466
  • HY-180087
    GABA-AT-IN-2

    		GABA Receptor Neurological Disease
    GABA-AT-IN-2 (compound 11g) is a GABA aminotransferase (GABA-AT) inhibitor with an IC50 of 19.8 μM. GABA-AT-IN-2 demonstrates notable antianxiety effects in mice. GABA-AT-IN-2 can be used for anxiety-related neurotic disorders research .
    GABA-AT-IN-2
  • HY-180372
    CSP-2503

    		5-HT Receptor Adrenergic Receptor GABA Receptor Serotonin Transporter Dopamine Receptor Neurological Disease
    CSP-2503 is a potent and selective 5-HT1A receptor agonist , with an EC50 of 0.15 μM and a Ki of 4.1 nM. CSP-2503 exhibits excellent selectivity over α1-adrenoceptors (Ki > 1000 nM), 5-HT4 receptors, and benzodiazepine receptors. CSP-2503 inhibits cAMP increase in vitro and exhibits anxiolytic activity in vivo. CSP-2503 can be used for the research of anxiety-related disorders .
    CSP-2503
  • HY-101834R
    ACT-462206 (Standard)

    		Reference Standards Orexin Receptor (OX Receptor) Others
    ACT-462206 (Standard) is the analytical standard of ACT-462206 (HY-101834). This product is intended for research and analytical applications. ACT-462206 is an orally active and potent dual Orexin 1/Orexin 2 receptor antagonist with IC50s of 60 nM (Orexin 1) and 11 nM (Orexin 2), respectively. ACT-462206 exhibits brain penetration properties, and can be used for insomnia, stress/anxiety-related disorders and addiction research .
    ACT-462206 (Standard)
  • HY-103505R
    CL 218872 (Standard)

    		Reference Standards GABA Receptor Neurological Disease
    CL 218872 (Standard) is the analytical standard of CL 218872 (HY-103505). This product is intended for research and analytical applications. CL 218872 is an orally active and selective ligand for the benzodiazepine receptor subtype BZ1. CL 218872 exhibits anxiolytic, sedative and anticonvulsant activities. CL 218872 can be used in researches of anxiety related disorders and epilepsy .
    CL 218872 (Standard)
  • HY-182677
    EF-7412

    		5-HT Receptor Dopamine Receptor Neurological Disease
    EF-7412 is a dual antagonist of the 5-HT1A receptor and dopamine D2 receptor, with Ki values of 27 nM and 22 nM, respectively. EF-7412 acts as an antagonist at both pre- and postsynaptic 5-HT1A receptor sites, blocking 8-OH-DPAT (HY-112061)-induced hypothermia, behavioral syndrome, and corticosterone elevation in vivo. EF-7412 increases hypothalamic 5-HIAA/5-HT and DOPAC/DA ratios, alters 5-HT and DA neuronal activity, and slightly decreases spontaneous motor activity. EF-7412 can be used for research on 5-HT1A/D2 receptor regulation and related neural pathways .
    EF-7412

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: