10 Results for "

cholera toxin

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "cholera toxin" in MCE Product Catalog:

13
13 Publications Verification
Cat. No.: HY-156131
CAS No.: 53179-11-6
Synonyms: ADL 2-1294
Loperamide (ADL 2-1294) is selective and orally active μ opioid receptor agonist with Ki valuess of 3, 48 and 1156 nM against μ, δ and κ opioid receptor, respectively. Loperamide produces antinociception and antihyperalgesia. Loperamide exhibits peripheral selectivity, enhancing fluid, electrolyte, and glucose absorption, reversing PGE2 (HY-101952)- and Cholera toxin (HY-P1446)-induced intestinal secretion, and reducing intestinal motility. Loperamide can be used for the researches of inflammatory pain and protracted diarrhoea .
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1 Cited Publications
Cat. No.: HY-112624I
CAS No.: 9004-54-0
Synonyms: Dextran 3; Dextran D3; Dextran T3(MW 2400-3600)
Dextran T3 (Dextran 3; Dextran T3(MW 2400-3600)) is a neural tracer and intestinal permeability probe that can move anterogradely and retrogradely in neuronal axons by passive diffusion. Dextran T3 (MW 3,000) is able to permeate across the intestinal epithelial cell membrane in the presence of cholera toxin-induced cytoskeletal disturbance. Dextran T3 (MW 3,000) is used as a fluorescent marker to rapidly label developing neurons (such as Xenopus retinal ganglion cells) and to assess intestinal barrier function. It can be used to study axonal transport in neuroanatomy and permeability changes in intestinal pathophysiology. The Dextran series of compounds are also natural polysaccharide drug carriers that can be connected to drugs through covalent bonding methods such as ester bonds, amide bonds or click chemistry, or self-assembled to form carriers such as nanoparticles and hydrogels. Dextran is biodegradable and biocompatible, and can achieve targeted delivery and controlled release of drugs. Dextran derivatives can prolong the half-life of drugs, increase local concentrations, and reduce the activity of immune clearance .
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1 Cited Publications
Cat. No.: HY-129040A
CAS No.: 87862-25-7
Purity:  99.78%
Synonyms: MIBG sulfate; Iobenguane sulfate
Target:  

Adrenergic Receptor

Research Areas:  

Cancer

m-Iodobenzylguanidine sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated m-Iodobenzylguanidine sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. m-Iodobenzylguanidine sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .
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Cat. No.: HY-P10529
CAS No.: 247185-97-3
Target:  

Trk Receptor

Research Areas:  

Infection

Ganglioside GM1-binding peptide p3 is a synthetic peptide that can specifically bind to the pentasaccharide part of GM1 ganglioside. The dynamic transformation of Ganglioside GM1-binding peptide p3 may play an important role in the function of GM1 as a multiple receptor, such as in the classical pathway of cholera toxin infection. Ganglioside GM1-binding peptide p3 can be used to study the interaction between GM1 and its ligands .
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Cat. No.: HY-401913
CAS No.: 345288-49-5
Research Areas:  

Infection Cancer

Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC50 is 4 μM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model .
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Cat. No.: HY-N10511
CAS No.: 67063-78-9
GM1a Ganglioside oligosaccharide is a semisynthetic form of ganglioside GM1. Ganglioside GM1 is the natural receptor for cholera toxin and plays an important role not only in general growth regulation but also in the coupling of hormone-induced responses .
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Cat. No.: HY-E70128
CAS No.: 9001-61-0
Target:  

Others

Research Areas:  

Others

Leucyl aminopeptidase, Porcine is a metallopeptidase that cleave N-terminal residues from proteins and peptides. Leucyl aminopeptidase serves as transcriptional repressors to control pyrimidine, alginate and cholera toxin biosynthesis, as well as mediate site-specific recombination events in plasmids and phages .
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Cat. No.: HY-129040AR
CAS No.: 87862-25-7
Synonyms: MIBG sulfate (Standard); Iobenguane sulfate (Standard)
Research Areas:  

Cancer

m-Iodobenzylguanidine (sulfate) (Standard) is the analytical standard of m-Iodobenzylguanidine (sulfate). This product is intended for research and analytical applications. m-Iodobenzylguanidine sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated m-Iodobenzylguanidine sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. m-Iodobenzylguanidine sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .
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Cat. No.: HY-165650
CAS No.: 165615-97-4
Synonyms: C16-GM1; N-Hexadecaoyl (13,13,14,14,15,15,16,16,16)-moosialogaglioside GM1
Target:  

Others

Research Areas:  

Infection

C16 Ganglioside GM1 (d18:1/16:0) (C16-GM1) is a member of the ganglioside family containing saturated C16:0 acyl chains. C16 Ganglioside GM1 (d18:1/16:0) serves as a functional receptor for Cholera toxin (HY-P1446) B subunit, while showing reduced efficiency in both transcytosis and retrograde pathways. C16 Ganglioside GM1 (d18:1/16:0) can be used for diarrheal diseases research .
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Cat. No.: HY-165650A
Synonyms: C16-GM1 ammonium; N-Hexadecaoyl (13,13,14,14,15,15,16,16,16)-moosialogaglioside GM1 ammonium
Target:  

Endogenous Metabolite

Research Areas:  

Infection

C16 Ganglioside GM1 (d18:1/16:0) (C16-GM1) ammonium is a member of the ganglioside family containing saturated C16:0 acyl chains. C16 Ganglioside GM1 (d18:1/16:0) ammonium serves as a functional receptor for Cholera toxin (HY-P1446) B subunit, while showing reduced efficiency in both transcytosis and retrograde pathways. C16 Ganglioside GM1 (d18:1/16:0) ammonium can be used for diarrheal diseases research .
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