derivatization

By Targets:	ADC Linker (2) Amino Acid Derivatives (1) Bcl-2 Family (1) Biochemical Assay Reagents (5) Fluorescent Dye (6) HIV (1) Insulin Receptor (2)
By Research Areas:	Cancer (3) Endocrinology (2) Infection (1) Metabolic Disease (2)
Click Chemistry:	TCO (2) Labeling and Fluorescence Imaging (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-136590

2-Nitrosopyridine 1 Publications Verification	Others	Others
2-Nitrosopyridine is a nitroso compound that can be used to synthesize antibiotics. 2-Nitrosopyridine can be used as a Click or Diels-Alder derivatization reagent and an excellent dienophile .

HY-W320397

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan	Fluorescent Dye	Others
4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.

HY-D0035

MPAC-Br

Fluorescent Dye Others

MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

MPAC-Br	Fluorescent Dye	Others
MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

HY-147232

N-Acryloyl-1-pyrenebutylamine	Fluorescent Dye	Others
N-Acryloyl-1-pyrenebutylamine is a potent fluorescent derivatization agent. N-Acryloyl-1-pyrenebutylamine combines with an alkyl-acrylamide side-chain to give fluorescence function on the polymer. .

HY-118469

Phanquinone 11925 C; Entronon	Others	Others
Phanquone (11925 C; Entronon) derives from a hydride of a 4,7-phenanthroline. Phanquone is applied as an original precolumn derivatization reagent for amino acids .

HY-138064

4-APC hydrobromide	Others	Others
4-APC hydrobromide is a highly sensitive and selective derivatization agent for aldehydes. 4-APC hydrobromide possesses an aniline moiety for a fast selective reaction with aliphatic aldehydes as well as a quaternary ammonium group for improved MS sensitivity. 4-APC hydrobromide allows highly sensitive and selective MS detection of aldehydes .

HY-131125

trans-4-Nitrocinnamoyl chloride

Biochemical Assay Reagents Others

trans-4-Nitrocinnamoyl chloride is used as derivatization reagent .
HY-156559

GlcNAc-SH

Biochemical Assay Reagents Others

GlcNAc-SH is a thiol-derivatized saccharide that can be used to label Dha to generate glycoprotein mimics .
HY-W014815

BPBA

2-Bromopyridine-5-boronic acid
Biochemical Assay Reagents Others

BPBA (2-Bromopyridine-5-boronic acid) is a new labeling reagent to derivatize brassinosteroids (BRs) .

trans-4-Nitrocinnamoyl chloride	Biochemical Assay Reagents	Others
trans-4-Nitrocinnamoyl chloride is used as derivatization reagent .

GlcNAc-SH	Biochemical Assay Reagents	Others
GlcNAc-SH is a thiol-derivatized saccharide that can be used to label Dha to generate glycoprotein mimics .

BPBA 2-Bromopyridine-5-boronic acid	Biochemical Assay Reagents	Others
BPBA (2-Bromopyridine-5-boronic acid) is a new labeling reagent to derivatize brassinosteroids (BRs) .

HY-101890

Dabsyl chloride 2 Publications Verification DABS-Cl	Fluorescent Dye	Others
Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.

HY-151682

H-L-Lys(Norbornene-methoxycarbonyl)-OH	ADC Linker	Others
H-L-Lys(Norbornene-methoxycarbonyl)-OH, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-151682A

H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride	ADC Linker	Others
H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-P2493

(Cys47)-HIV-1 tat Protein (47-57)	HIV	Others
(Cys47)-HIV-1 tat Protein (47-57) has membrane translocation function and can be used to derivatize the surface of magnetic pharmaceuticals and substantially facilitated their uptake into target cells .

HY-D1730

AF488 NHS ester	Fluorescent Dye	Others
AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization .

HY-161071

Antioxidant/anticancer agent 1	Others	Infection Cancer
Antioxidant/anticancer agent 1 (compound 5) is a pyrimidine-derivatized Schiff base based on pyrimidine hydroxy-1-naphthaldehyde and has antibacterial, antioxidant, antifungal, and anticancer properties. Antioxidant/anticancer agent 1 .

HY-D1254

Trx-red NBL-SS perchlorate	Fluorescent Dye	Others
Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .

HY-P3580

Acetyl Gastric Inhibitory Peptide (human) Human N-acetyl GIP	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity .

HY-P3580A

Acetyl Gastric Inhibitory Peptide (human) (TFA) Human N-acetyl GIP TFA	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research of diabetes, insulin resistance and obesity .

HY-149872

DCA-RMR1	Biochemical Assay Reagents	Others
DCA-RMR1 is a cross-linker. DCA-RMR1 elicits facile bicyclization of native peptides via N-terminus Cys-Cys cross-linking. DCA-RMR1 derivatizes RMR1 with 1,3-dichloroacetone (DCA) .

HY-W074541

Girard’s reagent T Trimethylacetohydrazideammonium chloride	Biochemical Assay Reagents	Others
Girard's reagent T is often used in analytical chemistry as a derivatizing agent for carbonyl compounds. Girard's reagent T reacts with ketones and aldehydes to form stable hydrazones that can be readily analyzed by various techniques including chromatography and spectrophotometry. In addition, Girard's Reagent T has been used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.

HY-Y0469

1-Aminohydantoin hydrochloride
1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection .

HY-141464

Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH Fmoc-Asn(Ac3AcNH-beta-Glc)-OH	Amino Acid Derivatives	Cancer
Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) can be used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET) .

HY-161242

CBI1	Bcl-2 Family	Cancer
CBI1 is a covalent BAX inhibitor. CBI1 selectively derivatizes BAX at C126 and inhibits BAX activation by triggering ligands or point mutagenesis. CBI1 blocks t-2-hex lipidation and oligomerization of BAX. CBI1 inhibits BAX activation induced by BH3 ligands, F116A mutagenesis or t-2-hex .

Cat. No.	Product Name	Type

HY-101890

Dabsyl chloride 2 Publications Verification DABS-Cl	Protein Labeling
Dabsyl chloride is an amine derivatizing agent, able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm; Dabsyl chloride also used for labeling amino acids.

HY-W320397

4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan	Fluorescent Dyes/Probes
4-(2-Aminoethylamino)-7-(N,N-dimethylsulfamoyl)benzofurazan is a precolumn fluorescence derivatization reagent.

HY-D0035

MPAC-Br

Fluorescent Dyes/Probes

MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

MPAC-Br	Fluorescent Dyes/Probes
MPAC-Br is a highly sensitive fluorescent derivatization reagent for carboxylic acids in HPLC .

HY-D1254

Trx-red NBL-SS perchlorate	Fluorescent Dyes/Probes
Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm) .

Cat. No.	Product Name	Type

HY-W074541

Girard’s reagent T Trimethylacetohydrazideammonium chloride	Biochemical Assay Reagents
Girard's reagent T is often used in analytical chemistry as a derivatizing agent for carbonyl compounds. Girard's reagent T reacts with ketones and aldehydes to form stable hydrazones that can be readily analyzed by various techniques including chromatography and spectrophotometry. In addition, Girard's Reagent T has been used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.

Girard’s reagent T

Trimethylacetohydrazideammonium chloride

Biochemical Assay Reagents

Girard's reagent T is often used in analytical chemistry as a derivatizing agent for carbonyl compounds. Girard's reagent T reacts with ketones and aldehydes to form stable hydrazones that can be readily analyzed by various techniques including chromatography and spectrophotometry. In addition, Girard's Reagent T has been used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.

Cat. No.	Product Name	Target	Research Area

HY-P3580A

Acetyl Gastric Inhibitory Peptide (human) (TFA) Human N-acetyl GIP TFA	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) TFA is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) TFA can be used for research of diabetes, insulin resistance and obesity .

HY-P2493

(Cys47)-HIV-1 tat Protein (47-57)	HIV	Others
(Cys47)-HIV-1 tat Protein (47-57) has membrane translocation function and can be used to derivatize the surface of magnetic pharmaceuticals and substantially facilitated their uptake into target cells .

HY-P3580

Acetyl Gastric Inhibitory Peptide (human) Human N-acetyl GIP	Insulin Receptor	Metabolic Disease Endocrinology
Acetyl Gastric Inhibitory Peptide (human) is a fatty acid derivatized analog of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Acetyl Gastric Inhibitory Peptide (human) can be used for research of diabetes, insulin resistance and obesity .

Cat. No.	Product Name		Classification

HY-151682

H-L-Lys(Norbornene-methoxycarbonyl)-OH		TCO Labeling and Fluorescence Imaging
H-L-Lys(Norbornene-methoxycarbonyl)-OH, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction .

HY-151682A

H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride		Labeling and Fluorescence Imaging TCO
H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride, a norbornene-derivatized lysine, can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride can be used for the mild and selective modification of proteins in a copper-free click reaction .

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Fluorescent Dye

Biochemical Assay Reagents

Peptides

Click Chemistry