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Cat. No.: HY-151682

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H-L-Lys(Norbornene-methoxycarbonyl)-OH

Name: H-L-Lys(Norbornene-methoxycarbonyl)-OH
Brand: MedChemExpress
SKU: HY-151682
Availability: PreOrder

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

H-L-Lys(Norbornene-methoxycarbonyl)-OH is a Norbornene (HY-W013021)-derivatized lysine that can be click-functionalized. H-L-Lys(Norbornene-methoxycarbonyl)-OH can be used for the mild and selective modification of proteins in a copper-free click reaction.

For research use only. We do not sell to patients.

CAS No.: 1378916-76-7
Formula: C₁₅H₂₄N₂O₄
Molecular Weight:296.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

H-L-Lys(Norbornene-methoxycarbonyl)-OH Chemical Structure

CAS No.: 1378916-76-7

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Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
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Biological Activity

Description

In Vitro

H-L-Lys(Norbornene-methoxycarbonyl)-OH undergoes copper-free click cycloaddition with nitrile imines and reversed-electron-demand Diels-Alder click reaction with tetrazines. H-L-Lys(Norbornene-methoxycarbonyl)-OH supports site-specific incorporation into fragile human proteins and peptides for chemical modification with rapid, high-yield quantitative conversion^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS No. 1378916-76-7
Molecular Weight 296.36
Formula C₁₅H₂₄N₂O₄
SMILES

OC([C@@H](N)CCCCNC(OCC1C2([H])CC(C=C2)([H])C1)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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iScience

8-azido-3,8-dideoxy-D-manno-octulosonic acid-mediated metabolic oligosaccharide engineering for specific labeling of diverse Enterobacterales. [Abstract]

2026 Mar 6;29(4):115255. PMID: 41907436

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kaya E, et al. A genetically encoded norbornene amino acid for the mild and selective modification of proteins in a copper‐free click reaction[J]. Angewandte Chemie International Edition, 2012, 51(18): 4466-4469. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

H-L-Lys(Norbornene-methoxycarbonyl)-OH

1 Cited Publications

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Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References

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H-L-Lys(Norbornene-methoxycarbonyl)-OH

Publications Citing Use of MedChemExpress (MCE) H-L-Lys(Norbornene-methoxycarbonyl)-OH