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Trx-red (Synonyms: NBL-SS perchlorate)

Cat. No.: HY-D1254
Handling Instructions

Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm).

For research use only. We do not sell to patients.

Trx-red Chemical Structure

Trx-red Chemical Structure

CAS No. : 2368978-96-3

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Description

Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm)[1].

In Vitro

Trx-red (NBL-SS) displayed multiple favorable properties, such as red emission, fast response, and high fluorescence signal. Thioredoxin (Trx) is a ubiquitous redox-regulating protein essentially involved in cell growth, differentiation, and death[1].
When HeLa cells are incubated with Trx-red (NBL-SS; 5 μM; 0-30 min), a clear time-dependent increase of the fluorescence is observed[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Trx-red (NBL-SS; 10 μM; 30 min) is also suitable to image thioredoxin in 6 day-old zebrafish larvae[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

714.16

Formula

C₂₉H₃₂ClN₃O₁₂S₂

CAS No.

2368978-96-3

SMILES

O=C(NC1=CC(OC2=C/3)=C(C4=C1C=CC=C4)N=C2C=CC3=[N+](CCC(OC)=O)/CCC(OC)=O)OCCSSCCO.O=Cl(=O)([O-])=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Trx-redNBL-SSOthersfluorescentprobethioredoxinlivecellsred-emittingInhibitorinhibitorinhibit

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