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Results for "

honeybee

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Peptides

2

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W592871
    10-Hydroxy-2-decenoic acid

    10-HDA

    		 mTOR Cardiovascular Disease Inflammation/Immunology Cancer
    10-Hydroxy-2-decenoic acid (10-HDA) is the major lipid component of royal jelly produced by honeybees. 10-Hydroxy-2-decenoic acid has several health-beneficial effects in mammals, such as antitumor activity, anti-inflammatory activity, and antiangiogenic activity. 10-Hydroxy-2-decenoic acid also extends the lifespan of C. elegans .
    10-Hydroxy-2-decenoic acid
  • HY-P5721
    Apidaecin IA

    		Bacterial Infection
    Apidaecin IA is an antibacterial peptide that can be found in honeybees .
    Apidaecin IA
  • HY-B0827B
    (S)-Dinotefuran

    (S)-MTI-446

    		 nAChR Parasite Infection
    (S)-Dinotefuran ((S)-MTI-446), a neonicotinoid pesticide, is toxic by binding to α8 subunit of nAChR of honeybee Apis mellifera (Apis mellifera Linnaeus). (S)-Dinotefuran shows more toxic than R-dinotefuran to honeybee Apis mellifera .
    (S)-Dinotefuran
  • HY-B0827A
    (R)-Dinotefuran

    (R)-MTI-446

    		 nAChR Parasite Infection
    (R)-Dinotefuran ((R)-MTI-446), a neonicotinoid pesticide, exhibits comparative insecticidal activities (1.7-2.4 times) to typical sucking pests Aphis gossypii and Apolygus lucorum compared to racemic mixtures by inhibiting nicotinic acetylcholine receptors. (R)-Dinotefuran has a good efficacy in controlling target pests while minimizing hazard to honeybees .
    (R)-Dinotefuran
  • HY-P3906
    Melittin free acid

    		Fungal Apoptosis Phospholipase Reactive Oxygen Species Infection
    Melittin free acid is a basic 26-amino-acid polypeptide, the major active ingredient of honeybee venom. Melittin free acid is an activator of phospholipase A2 (PLA2). Melittin free acid has broad-spectrum antifungal activity with MIC values of 0.4-60 μM. Melittin free acid hinders fungal growth by inducing cell apoptosis, repressing (1,3)-β-D-glucan synthase and participating in other pathways .
    Melittin free acid
  • HY-156339
    GABA receptor Antagonist 1

    		GABA Receptor Others
    GABA receptor Antagonist 1 (compound 7w) inhibits Px RDL1 GABAR with an IC50 value of 7.08 nmol/L. GABA receptor Antagonist 1 shows insecticide activity against P. xylostella, S. frugiperda, S. exigua, and S. litura, with LC50 of 0.09, 0.84, 0.87, and 0.68 mg/L respectively. GABA receptor Antagonist 1 shows a medium toxicity to honeybee (48 h, ID50 = 2.22 μg/adult), and low toxicity to zebrafish (LC50: 42.4 mg/L) .
    GABA receptor Antagonist 1

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