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Results for "

human PCNA

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Biochemical Assay Reagents

1

Peptides

2

Recombinant Proteins

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-NP199
    Bovine pituitary extract
    1 Publications Verification

    		 Reactive Oxygen Species (ROS) Inflammation/Immunology
    Bovine pituitary extract is a bovine pituitary extract that can be used as a mitogenic supplement in serum-free growth media. Bovine pituitary extract is rich in growth factors. Bovine pituitary extract not only promotes the proliferation of corneal keratinocytes and maintains their phenotype, but also exerts significant antioxidant stress protective effects on human prostate epithelial cells .
    Bovine pituitary extract
  • HY-125576
    Griselimycin

    		Bacterial Infection
    Griselimycin is a cyclic lipopeptide produced by Streptomyces. Griselimycin specifically binds to the sliding clamp of bacterial DNA polymerase and does not interact with human PCNA. Griselimycin exhibits potent antibacterial activity against Mycobacterium tuberculosis (including drug-resistant strains) and a variety of Gram-negative bacteria .
    Griselimycin
  • HY-RS10159
    PCNA Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PCNA Human Pre-designed siRNA Set A contains three designed siRNAs for PCNA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PCNA Human Pre-designed siRNA Set A
    PCNA Human Pre-designed siRNA Set A
  • HY-183363
    USP1-IN-17

    		Deubiquitinase Cancer
    USP1-IN-17 is an orally active USP1/UAF1 complex inhibitor. USP1-IN-17 exhibits potent anti-proliferative activity against BRCA1-mutant human breast cancer MDA-MB-436 cells, with an IC50 value of 8.1 nM. USP1-IN-17 binds to USP1 to stabilize the enzyme conformation, impairs deubiquitination function, elevates the monoubiquitination level of PCNA, inhibits cancer cell proliferation, and induces DNA damage accumulation. USP1-IN-17 can be used for the research of BRCA1-mutated cancers .
    USP1-IN-17
  • HY-183581
    USP1-IN-18

    		Deubiquitinase DNA/RNA Synthesis Cancer
    USP1-IN-18 is an orally active USP1 inhibitor with a human IC50 of 17.0 nM. USP1-IN-18 inhibits USP1-UAF1 deubiquitinase activity and drives ubiquitinated PCNA accumulation. USP1-IN-18 induces DNA damage, replication stress, and G2-M phase cell cycle arrest. USP1-IN-18 can be used for the research of triple-negative breast cancer .
    USP1-IN-18

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