Bovine pituitary extract
Based on 1 publication(s) in Google Scholar
Bovine pituitary extract is a bovine pituitary extract that can be used as a mitogenic supplement in serum-free growth media. Bovine pituitary extract is rich in growth factors. Bovine pituitary extract not only promotes the proliferation of corneal keratinocytes and maintains their phenotype, but also exerts significant antioxidant stress protective effects on human prostate epithelial cells.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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- References
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Publications Citing Use of MedChemExpress (MCE) Bovine pituitary extract
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Biological Activity
Bovine pituitary extract (50 μg/mL; 24 h) significantly protects RWPE-1 human prostate epithelial cells against H2O2-induced cell death and maintains the intact structure of cell membranes and cytoplasm[1].
Bovine pituitary extract (50 μg/mL; 6 h) significantly reduces H2O2-induced protein oxidation in RWPE-1 human prostate epithelial cells[1].
Bovine pituitary extract (50 μg/mL; 6 h) inhibits H2O2-induced DNA fragmentation and necrosis in the human prostatic epithelial cell line RWPE-1[1].
Bovine pituitary extract (50 μg/mL; 4 h) enhances intracellular ROS accumulation induced by H2O2 in RWPE-1 human prostate epithelial cells[1].
Bovine pituitary extract (50 μg/mL; 14 d) promotes the proliferation of human corneal stromal cells and maintains their dendritic, non-fibroblastic phenotype during 14 days of primary culture[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Nontumorigenic human prostate epithelial RWPE-1 cells
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Concentration:50 μg/mL
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Incubation Time:24 h (concurrent with H2O2 exposure)
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Result:Provided significant protection against H2O2-induced cell death, maintaining high cell viability even after treatment with 200, 400, and 800 μM H2O2.
Chemical Information
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Appearance Liquid
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Color Light brown to brown
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SMILES
[Bovine pituitary extract]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Biochem Biophys Res Commun
Nicotinic acetylcholine receptors modulate casein secretion and claudin expression in mammary epithelial cells by regulating STAT5 and Akt pathways. [Abstract]2025 May 15:770:152036. PMID: 40382844
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Kent KD, et al. Bovine pituitary extract provides remarkable protection against oxidative stress in human prostate epithelial cells. In Vitro Cell Dev Biol Anim. 2003;39(8-9):388-394. [Content Brief]
[2]. Xu ZZ, et al. Using bovine pituitary extract to increase proliferation of keratocytes and maintain their phenotype in vitro. Int J Ophthalmol. 2013;6(6):758-765. Published 2013 Dec 18. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bovine pituitary extract Related Classifications
HY-NP199 Related Classifications
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