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hyperphosphatemia

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13995A
    Sevelamer hydrochloride
    1 Publications Verification

    		 FXR Autophagy Others
    Sevelamer hydrochloride is an orally active and phosphate binding agent used for research of hyperphosphatemia with chronic kidney disease. Sevelamer hydrochloride consists of polyallylamine that is crosslinked with epichlorohydrin .
    Sevelamer hydrochloride
  • HY-15991
    Tenapanor
    4 Publications Verification

    AZD1722; RDX5791

    		 Na+/H+ Exchanger (NHE) Metabolic Disease
    Tenapanor (AZD1722) is a potent and orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor reduces intestinal phosphate absorption predominantly through reduction of passive paracellular phosphate flux. Tenapanor has the potential for the research of hyperphosphatemia .
    Tenapanor
  • HY-15991A
    Tenapanor hydrochloride
    4 Publications Verification

    AZD1722 hydrochloride; RDX5791 hydrochloride

    		 Na+/H+ Exchanger (NHE) Metabolic Disease
    Tenapanor (AZD1722) hydrochloride is a potent and orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor hydrochloride reduces intestinal phosphate absorption predominantly through reduction of passive paracellular phosphate flux. Tenapanor hydrochloride has the potential for the research of hyperphosphatemia .
    Tenapanor hydrochloride
  • HY-146429
    NaPi2b-IN-3

    		Others Metabolic Disease
    NaPi2b-IN-3 (compound 5) is a potent sodium-dependent transport protein 2b (SLC34A2, NaPi2b) inhibitor with IC50s of 71 nM and 28 nM for human NaPi2b and rat NaPi2b, respectively. NaPi2b-IN-3 can be used for researching hyperphosphatemia .
    NaPi2b-IN-3
  • HY-142957
    NaPi2b-IN-1

    		Others Others
    NaPi2b-IN-1 is a potent and orally active inhibitor of sodium-dependent phosphate transport protein 2b (NaPi2b) with an IC50 of 64 nM. NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. NaPi2b-IN-1 has the potential for the research of hyperphosphatemia .
    NaPi2b-IN-1
  • HY-145894
    NaPi2b-IN-2

    		Others Others
    NaPi2b-IN-2 (compound 5) is a potent inhibitor of sodium-dependent transport protein 2b (SLC34A2, NaPi2b), with an IC50 of 38 nM for human NaPi2b. NaPi2b-IN-2 can be used for the research of hyperphosphatemia .
    NaPi2b-IN-2
  • HY-13995
    Sevelamer

    		FXR Autophagy Endocrinology
    Sevelamer is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin.
    Sevelamer
  • HY-13995B
    Sevelamer carbonate
    1 Publications Verification

    		 Others Metabolic Disease
    Sevelamer carbonate is an orally active and non-calcium-based phosphate binding agent and used for the hyperphosphatemia of chronic kidney disease (CKD)research. Sevelamer carbonate effectively lowers serum phosphorus levels hile having minimal effect on serum calcium or serum chloride levels in vivo. Sevelamer carbonate is considered as an improved, buffered form of sevelamer (HY-13995) .
    Sevelamer carbonate
  • HY-N1428C
    Ferric citrate
    1 Publications Verification

    Iron(III) citrate; Zerenex

    		 Reactive Oxygen Species Antibiotic Metabolic Disease
    Ferric citrate (Iron(III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research .
    Ferric citrate

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