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inert

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8

Inhibitors & Agonists

1

Peptides

1

Inhibitory Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0227

    Tris; Tris(hydroxymethyl)aminomethane

    Biochemical Assay Reagents Metabolic Disease Cancer
    THAM (Tris) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM is an effective amine compound for pH control in the physiological range .
    THAM
  • HY-133105

    Oxothiazolidinecarboxylic acid

    Others Inflammation/Immunology
    Procysteine, an antioxidant, is a proagent of cysteine that is inert until metabolized to cysteine intracellulary, thus stimulating glutathione synthesis .
    Procysteine
  • HY-D0227B

    Tris acetate; Tris(hydroxymethyl)aminomethane acetate

    Trometamol acetate (Tromethamine acetate) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol acetate is an effective amine compound for pH control in the physiological range .
    THAM acetate
  • HY-16215

    G-202

    Drug-Linker Conjugates for ADC Cancer
    Mipsagargin (G-202) is a novel thapsigargin-based targeted proagent consisting of a prostate-specific membrane antigen (PSMA)-specific peptide coupled to an analog of the potent sarcoplasmic/endoplasmic reticulum calcium adenosine triphosphatase (SERCA) pump inhibitor Thapsigargin (HY-13433). Mipsagargin is activated by PSMA-mediated cleavage of an inert masking peptide. Mipsagargin has the potential for refractory, advanced or metastatic solid tumours research .
    Mipsagargin
  • HY-131039

    MDNI-glu

    Amino Acid Derivatives Others
    MDNI-caged-L-glutamate (MDNI-glu) is a biologically inert, photosensitive derivative of the major excitatory amino acid, L-glutamate. MDNI-caged-L-glutamate makes more efficient use of incident light .
    MDNI-caged-L-glutamate
  • HY-D0227A

    Tris HCl; Tris(hydroxymethyl)aminomethane hydrochloride

    THAM hydrochloride (Tris HCl) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. THAM hydrochloride is an effective amine compound for pH control in the physiological range .
    THAM hydrochloride
  • HY-P99572

    BNT-312; DuoBody-CD40x-4-1BB; GEN1042

    TNF Receptor Inflammation/Immunology Cancer
    Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity .
    Tecaginlimab
  • HY-111373
    RapaLink-1
    5 Publications Verification

    mTOR Autophagy Cancer
    RapaLink-1, the third-generation bivalent mTOR inhibitor, combines Rapamycin (HY-10219) with MLN0128 (HY-13328, a second-generation mTOR kinase inhibitor) by an inert chemical linker. RapaLink-1 shows better efficacy than Rapamycin or mTOR kinase inhibitors (TORKi), potently blocking cancer-derived, activating mutants of mTOR. RapaLink-1 can cross the blood-brain barrier. RapaLink-1 binding to FKBP12 results in targeted and durable inhibition of mTORC1. RapaLink-1 plays an antithrombotic role in antiphospholipid syndrome by improving autophagy. Anticancer activity .
    RapaLink-1

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