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Trometamol hydrochloride (Synonyms: Tromethamine hydrochloride)

Cat. No.: HY-D0227A
Handling Instructions

Trometamol hydrochloride (Tromethamine hydrochloride) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol hydrochloride is an effective amine compound for pH control in the physiological range.

For research use only. We do not sell to patients.

Trometamol hydrochloride Chemical Structure

Trometamol hydrochloride Chemical Structure

CAS No. : 1185-53-1

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Description

Trometamol hydrochloride (Tromethamine hydrochloride) is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol hydrochloride is an effective amine compound for pH control in the physiological range[1].

Molecular Weight

157.60

Formula

C₄H₁₂ClNO₃

CAS No.

1185-53-1

SMILES

OCC(CO)(N)CO.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1586.29 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.3452 mL 31.7259 mL 63.4518 mL
5 mM 1.2690 mL 6.3452 mL 12.6904 mL
10 mM 0.6345 mL 3.1726 mL 6.3452 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 4.17 mg/mL (26.46 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 4.17 mg/mL (26.46 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 4.17 mg/mL (26.46 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

TrometamolTromethamineOthersinertaminopHcontrolacidaemiaInhibitorinhibitorinhibit

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Trometamol hydrochloride
Cat. No.:
HY-D0227A
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