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insect juvenile hormone activity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) c-Met/HGFR (1) Drug Intermediate (1) Isotope-Labeled Compounds (1) Parasite (1)
By Research Areas:	Infection (1) Metabolic Disease (1)

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Isotope-Labeled Compounds

Targets Recommended: Thyroid Hormone Receptor PTHR GHR Nuclear Hormone Receptor 4A/NR4A TSH Receptor MCHR1 (GPR24) GHSR Hormone-Sensitive Lipase (HSL) GnRH Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7240

(Rac)-Juvenile hormone III	Others	Metabolic Disease
(Rac)-Juvenile hormone III is a cecropia juvenile hormone and juvenile hormone agonist. (Rac)-Juvenile hormone III induces test insects to retain larval characteristics after the final molt to the adult stage. (Rac)-Juvenile hormone III exhibits juvenile hormone activity in Tenebrio molitor pupae and last-instar nymphs of Oncopeltus fasciatus. (Rac)-Juvenile hormone III possesses morphogenetic activity in insect assays .

HY-N7240S

(Rac)-Juvenile Hormone III-d3	Isotope-Labeled Compounds Others	Others
Juvenile Hormone III-d₃ is the deuterium labeled Juvenile Hormone III. (Rac)-Juvenile Hormone III is a cecropia juvenile hormone and juvenile hormone agonist. (Rac)-Juvenile Hormone III induces test insects to retain larval characteristics after the final molt to the adult stage. (Rac)-Juvenile Hormone III exhibits juvenile hormone activity in Tenebrio molitor pupae and last-instar nymphs of Oncopeltus fasciatus. (Rac)-Juvenile Hormone III possesses morphogenetic activity in insect assays .

HY-W587689

Juvenile hormone B 3 (mixture of diastereomers) juvenile hormone III bisepoxide; juvenile hormone bisepoxide; JHB3	c-Met/HGFR	Others
Juvenile hormone B 3 (Juvenile hormone III bisepoxide)(mixture of diastereomers) is a sesquiterpenoid hormone. Juvenile hormone B 3 can be isolated from corpus allatum (CA) of high dipterans like the fruitfly and Drosophila melanogaster. JHB3 has anti-metamorphic activity and induces Kr-h1 expression by directly interacting with juvenile hormone (JH) receptors (Met and Gce). Juvenile hormone B 3 can be used for insect lethality research .

HY-P10390

Insecticidal agent 11	Parasite	Infection
Insecticidal agent 11 (compound Q6) is a potent *insect* growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella .

HY-N20623

(+)-Todomatuic acid	Drug Intermediate	Others
(+)-Todomatuic acid is a naturally occurring sesquiterpenoid, and its derivatives juvabiones exhibit juvenile hormone-like activity in insects as well as antifungal activity. (+)-Todomatuic acid can be used in research on the regulation of agricultural pests and the inhibition of phytopathogenic fungi .

HY-W340857

Farnesane 2,6,10-Trimethyldodecane; Hemisqualane	Biochemical Assay Reagents	Others
Farnesane (2,6,10-Trimethyldodecane; Hemisqualane) is an isoprenoid derivative. Farnesane can be used to modulate juvenile hormone activity in insects .

Cat. No.	Product Name	Target	Research Area

HY-P10390

Insecticidal agent 11	Parasite	Infection
Insecticidal agent 11 (compound Q6) is a potent *insect* growth regulator (IGR)-based insecticide. Insecticidal agent 11 shows high insecticidal activity against Diploptera punctata by inhibiting juvenile hormone (JH) biosynthesis. Insecticidal agent 11 also exhibits insecticidal activity against Plutella xylostella .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N7240

(Rac)-Juvenile hormone III	Structural Classification Natural Products Animals Source Classification	Others
(Rac)-Juvenile hormone III is a cecropia juvenile hormone and juvenile hormone agonist. (Rac)-Juvenile hormone III induces test insects to retain larval characteristics after the final molt to the adult stage. (Rac)-Juvenile hormone III exhibits juvenile hormone activity in Tenebrio molitor pupae and last-instar nymphs of Oncopeltus fasciatus. (Rac)-Juvenile hormone III possesses morphogenetic activity in insect assays .

HY-N20623

(+)-Todomatuic acid	Structural Classification Pinaceae Ketones, Aldehydes, Acids Plants Abies sachalinensis (F.Schmidt) Mast. Source Classification	Drug Intermediate
(+)-Todomatuic acid is a naturally occurring sesquiterpenoid, and its derivatives juvabiones exhibit juvenile hormone-like activity in insects as well as antifungal activity. (+)-Todomatuic acid can be used in research on the regulation of agricultural pests and the inhibition of phytopathogenic fungi .

Cat. No.	Product Name	Chemical Structure

HY-N7240S

(Rac)-Juvenile Hormone III-d3
Juvenile Hormone III-d₃ is the deuterium labeled Juvenile Hormone III. (Rac)-Juvenile Hormone III is a cecropia juvenile hormone and juvenile hormone agonist. (Rac)-Juvenile Hormone III induces test insects to retain larval characteristics after the final molt to the adult stage. (Rac)-Juvenile Hormone III exhibits juvenile hormone activity in Tenebrio molitor pupae and last-instar nymphs of Oncopeltus fasciatus. (Rac)-Juvenile Hormone III possesses morphogenetic activity in insect assays .

(Rac)-Juvenile Hormone III-d3

Juvenile Hormone III-d₃ is the deuterium labeled Juvenile Hormone III. (Rac)-Juvenile Hormone III is a cecropia juvenile hormone and juvenile hormone agonist. (Rac)-Juvenile Hormone III induces test insects to retain larval characteristics after the final molt to the adult stage. (Rac)-Juvenile Hormone III exhibits juvenile hormone activity in Tenebrio molitor pupae and last-instar nymphs of Oncopeltus fasciatus. (Rac)-Juvenile Hormone III possesses morphogenetic activity in insect assays .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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