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lysosomal acid sterol ester hydrolase

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1)
By Research Areas:	Metabolic Disease (1)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Targets Recommended: Carboxylesterase (CES) CETP Hormone-Sensitive Lipase (HSL) Epoxide Hydrolase FAAH S-adenosylhomocysteine hydrolase (SAHH) OGA

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112487

Sandoz 58-035	Acyltransferase	Metabolic Disease
Sandoz 58-035 is a selective acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. Sandoz 58-035 inhibits this enzyme in intact cells and isolated microsomal fractions. Sandoz 58-035 blocks the esterification of exogenous vesicle-derived cholesterol and the incorporation of oleic acid into cellular cholesterol esters, reducing the formation and accumulation of cholesterol esters. Sandoz 58-035 causes a slight increase in cellular free cholesterol, and at high concentrations, it also causes a slight reduction in overall cellular protein synthesis. Sandoz 58-035 can be used in studies related to cellular cholesterol regulation .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P703648

	LIPA Protein, Human (P. pastoris, His) lysosomal acid lipase/cholesteryl ester hydrolase; Cholesteryl esterase; Diacylglycerol lipase; sterol esterase	Human	P. pastoris
	LIPA Protein, Human (P. pastoris, His) is the recombinant human-derived LIPA protein, expressed by P. pastoris, with N-6*His tag.

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Host:	Mouse (2)
Reactivity:	Human (2)
Application:	WB (2) ELISA (2)
Isotype:	IgG2a (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

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HY-P85252

	LAL Antibody (YA4944) LIPA; lysosomal acid lipase/cholesteryl ester hydrolase; acid cholesteryl ester hydrolase; LAL; Cholesteryl esterase; Lipase A; sterol esterase	WB, ELISA	Human
	LAL Antibody (YA4944) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to LAL.

HY-P85252A

	LAL Antibody (YA4944)(PBS only) LIPA; lysosomal acid lipase/cholesteryl ester hydrolase; acid cholesteryl ester hydrolase; LAL; Cholesteryl esterase; Lipase A; sterol esterase	WB, ELISA	Human
	LAL Antibody (YA4944) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to LAL.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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