Search Result

Search Result

Results for "

marmoset

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Dopamine Receptor (1) Interleukin Related (1) Monoamine Oxidase (1) Oxytocin Receptor (2) Renin (1)
By Research Areas:	Cardiovascular Disease (1) Endocrinology (2) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (2)

7

Inhibitors & Agonists

2

Peptides

1

Inhibitory Antibodies

5

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

NGD94-1	Dopamine Receptor	Neurological Disease
NGD94-1 is a specific dopamine D₄ receptor antagonist. NGD94-1 can effectively reverse Phencyclidine-induced cognitive impairment in marmosets. NGD94-1 can be used in the study of psychiatric diseases .

Canakinumab Ilaris; ACZ 885	Interleukin Related	Inflammation/Immunology
Canakinumab (ACZ885) is a recombinant human anti-IL-1β monoclonal antibody. Canakinumab shows IC₅₀ values of 43.6 and 40.8 pM for human and marmoset IL-1β, respectively. The mode of action of canakinumab is based on the neutralization of IL-1β signaling, resulting in suppression of inflammation related to disorders of autoimmune origin .

Pro8-Oxytocin	Oxytocin Receptor	Endocrinology
Pro8-Oxytocin is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin produce a less efficacious response than Vasopressin (HY-B1811) (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a .

Squalene synthase-IN-2	Others	Metabolic Disease
Squalene synthase-IN-2 (comppund isomer A-(1S, 3R)-14i) is an orally active squalene synthase inhibitor with IC₅₀ values of 3.4, 99 nM for squalene synthase and cholesterol synthesis, respectively. Squalene synthase-IN-2 reduces plasma cholesterol and triglyceride .

Remikiren Ro 42-5892; Ro 42-5892/001	Renin	Cardiovascular Disease
Remikiren (Ro 42-5892) is an orally active and highly specific renin inhibitor. Remikiren specifically inhibits human reninand human plasma renin with IC₅₀ values of 0.7 and 0.8 nM, respectively. Remikiren also reduces mean arterial blood pressure in sodium-depleted marmosets and squirrel monkeys. Remikiren can be used in study of hypertension .

Brasofensine sulfate BMS-204756 sulfate	Monoamine Oxidase	Neurological Disease
Brasofensine (BMS-204756) sulfate is a dopamine transporter antagonist and can be used for parkinson’s disease research .

Pro8-Oxytocin TFA	Oxytocin Receptor	Endocrinology
Pro8-Oxytocin TFA is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin TFA produce a less efficacious response than Vasopressin (HY-B1811) (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a .

Species:	Marmoset (5)
Tag:	His (3) Tag Free (1) Fc (1)
Source:	HEK293 (4) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

	*LAG-3 Protein, Marmoset* (HEK293, His)** LAG3; CD223; FDC	Marmoset	HEK293
	LAG-3 (lymphocyte activation gene 3) protein is expressed on antigen-activated T cells and transmits inhibitory signals by binding to ligands such as FGL1. FGL1 is the main ligand responsible for the suppressive function of LAG3 T cells. LAG-3 Protein, Marmoset (HEK293, His) is the recombinant Marmoset-derived LAG-3 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of LAG-3 Protein, Marmoset (HEK293, His) is 432 a.a., with molecular weight of ~57 kDa.

	*IL-12 beta Protein, Marmoset* (HEK293, Fc)** Interleukin-12 subunit beta; IL-12B; CLMF p40; IL-12 subunit p40; NKSF2; IL12B	Marmoset	HEK293
	IL-12 beta Protein, also known as natural killer cell stimulatory factor 2, is a common subunit (p40) of IL-12 and IL-23. IL-12 is a inflammatory factor expressed by activated macrophages, and involves in Th1-type immune response against cancer. IL-12 beta Protein located outside the cell membrane, involves in singalling mediated by Jak-STAT. IL-12 beta Protein consists of 335 amino acids (M1-N328) with a fibronectin type-III domain (233-324 a.a). IL-12 beta Protein, Marmoset is produced in HEK293 cells with a C-Terminal hFc-tag.

	*TIM-3/HAVCR2 Protein, Marmoset* (HEK293, His)** Hepatitis A virus cellular receptor 2 homolog; T cell immunoglobulin and mucin domain3; HAVCR2; CD366; TIM3	Marmoset	HEK293
	TIM-3/HAVCR2 Protein is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM-3/HAVCR2 Protein, Marmoset (HEK293, His) is the recombinant Marmoset-derived TIM-3/HAVCR2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TIM-3/HAVCR2 Protein, Marmoset (HEK293, His) is 170 a.a., with molecular weight of 30-45 kDa.

	IL-17A Protein, Marmoset Interleukin-17A; IL-17; IL-17A; Cytotoxic T-Lymphocyte-Associated Antigen 8; CTLA-8; IL17A; CTLA8; IL17	Marmoset	E. coli
	IL-17A is a homodimeric cytokine and plays a critical role in host defense mechanisms against many bacterial and fungal pathogens as well as allergic and autoimmune responses. IL-17A induces the production of antimicrobial peptides, cytokines, chemokines, and matrix metalloproteinases. IL-17A Protein, Marmoset is a recombinant marmoset IL-17A protein is expressed in E. coli. It consists of 134 amino acids (I20-A153).

	*IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset* (HEK293, His)** IL-23 p19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF	Marmoset	HEK293
	IL-23 alpha protein, a member of the IL-6 superfamily, is featured. IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset (HEK293, His) is a recombinant protein dimer complex containing Marmoset-derived IL-23 alpha & IL-12 beta Heterodimer protein, expressed by HEK293 , with C-His labeled tag. IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset (HEK293, His), has molecular weight of ~22 & 45 kDa, respectively.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

MedChemExpress Magic Cece

MedChemExpress: Contact Us; About Us; Headquarters; Distributors; Statement on False Report; Careers

Customer Support: Technical Support; Service; Ordering Information; Easy Return; Shipping Rates & Policies; Intellectual Property Promise

Resources: Free Sample; Resources; Molarity Calculator; Dilution Calculator; Terms & Conditions; Reconstitution Calculator; Specific Activity Calculator

Subscribe to our E-newsletter

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

Copyright © 2013-2024 MedChemExpress. All Rights Reserved.: Site Map Privacy Policy

Join with us