2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-23
  6. IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset (HEK293, His)

IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset (HEK293, His)

Cat. No.: HY-P73194
Handling Instructions

IL-23 alpha protein, a member of the IL-6 superfamily, is featured. IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset (HEK293, His) is a recombinant protein dimer complex containing Marmoset-derived IL-23 alpha & IL-12 beta Heterodimer protein, expressed by HEK293 , with C-His labeled tag. IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset (HEK293, His), has molecular weight of ~22 & 45 kDa, respectively.

For research use only. We do not sell to patients.

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Description

IL-23 alpha protein, a member of the IL-6 superfamily, is featured. IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset (HEK293, His) is a recombinant protein dimer complex containing Marmoset-derived IL-23 alpha & IL-12 beta Heterodimer protein, expressed by HEK293 , with C-His labeled tag. IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset (HEK293, His), has molecular weight of ~22 & 45 kDa, respectively.
Background

IL-23 alpha Protein belongs to the IL-6 superfamily.
Species

Marmoset
Source

HEK293
Tag

C-His
Accession

A0A2R8N533 (R20-P189)&XP_035133514.2 (I23-N328)
Gene ID

100414179  [NCBI]
Molecular Construction
N-term
IL23A (R20-P189)
Accession # A0A2R8N533
10*His
C-term
N-term
IL12B (I23-N328)
Accession # XP_035133514.2
10*His
C-term
Synonyms
IL-23 p19/IL-12 p40; IL23; IL-23A; Interleukin 23; SGRF
AA Sequence

IL23A:
RAVPGGSSPAWTQCQQLSQKLCMLAWSAHPLVGHMHLREEGDEETTNDVPHIQCGDGCDPQGLRDNSQFCLQRIHQGLIFYEKLLGSDIFTGEPSLLPDSPVGQLHASLLGLSQLLQPEGHHWETQQIPSPGPSQPWQRLLLRFKILRSLQAFVAVAARV
FAHGAATLSP IL12B:
IWELKKDVYVIELDWYLDAPGEMVVITCDTPEEDGITWTLEESSEVLGSGKNLTIQVKEFGDAGQYTCHKGGEALSHLLLLLHKKEDGVWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPRGVMCGAPVLSAERVRADGKEYEYSVECQEDSACPAAEERLPIEVVVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCIQVQGKSKREKKDRVFMDKTSATVICRKNASVSVQAQDRYYSSSWSEWASVPCN

Molecular Weight

Approximately 22&45 kDa
Purity

Greater than 85% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IL-23 alpha & IL-12 beta Heterodimer Protein, Marmoset (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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