IL-12 beta
Interleukin-12 subunit beta (IL-12B, commonly p40) is the 40 kDa shared subunit of two distinct heterodimeric cytokines: IL-12 (paired with p35/IL-12A) and IL-23 (paired with p19/IL-23A). Structurally it comprises two fibronectin type III domains, an Ig-like domain and a WSXWS motif, resembling a soluble cytokine receptor fused to a cytokine chain. p40 is produced by dendritic cells, macrophages, B cells and neutrophils after TLR or CD40 stimulation, and is additionally secreted as a monomer and disulfide-linked homodimer (p80) with distinct functions: p40 monomer antagonizes IL-12 signaling, p80 signals through IL-12Rβ1 to drive TNF and nitric oxide production in macrophages and neuropathic pain. Polymorphisms in IL12B influence susceptibility to tuberculosis, type 1 diabetes and psoriasis; the anti-p40 antibody ustekinumab blocks both IL-12 and IL-23 and is highly effective in psoriasis and Crohn's disease.
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IL-12 beta Recombinant Proteins (26)
IL-12 Protein, Human (HEK293, His)
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Cat. No.: HY-P73898
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12A; Cytotoxic Lymphocyte Maturation Factor 1, P35; Prev. NKSF1; NK Cell Stimulatory Factor Chain 1; IL-12A; Interleukin-12 Alpha Chain; Interleukin-12 Subunit Alpha; Interleukin 12, P35; CLMF; IL-12, Subunit P35; NFSK; IL35 Subunit; P35; CLMF P35; Inte
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IL-12 beta Protein, Human (HEK293, Fc)
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Cat. No.: HY-P73160
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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GMP IL-12 Protein, Human (HEK293, His)
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Cat. No.: HY-P73156
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12A; Cytotoxic Lymphocyte Maturation Factor 1, P35; Prev. NKSF1; NK Cell Stimulatory Factor Chain 1; IL-12A; Interleukin-12 Alpha Chain; Interleukin-12 Subunit Alpha; Interleukin 12, P35; CLMF; IL-12, Subunit P35; NFSK; IL35 Subunit; P35; CLMF P35; Interleukin 12A (Natural Killer Cell Stimulatory Factor 1, Cytotoxic Lymphocyte Maturation Factor 1, P35); Natural Killer Cell Stimulatory Factor 1, 35 KD Subunit; Cytotoxic Lymphocyte Maturation Factor 35 KDa Subunit; IL-12 Subunit P35; Interleukin 12A; NF Cell Stimulatory Factor Chain 1; IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40); Natural Killer Cell Stimulatory Factor-2; Natural Killer Cell Stimulatory Factor, 40 KD Subunit; Truncated Interleukin 12B; Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit; IMD29; NK Cell Stimulatory Factor Chain 2; IMD28; Interleukin 12B; Interleukin-12 Beta Chain
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Animal-Free IL-12 Protein, Human (HEK293, His)
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Cat. No.: HY-P700101AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12A; Cytotoxic Lymphocyte Maturation Factor 1, P35; Prev. NKSF1; NK Cell Stimulatory Factor Chain 1; IL-12A; Interleukin-12 Alpha Chain; Interleukin-12 Subunit Alpha; Interleukin 12, P35; CLMF; IL-12, Subunit P35; NFSK; IL35 Subunit; P35; CLMF P35; Inte
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IL-12 beta Protein, Human (HEK293)
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Cat. No.: HY-P70617
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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IL-12 Protein, Mouse (HEK293, His)
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Cat. No.: HY-P73159
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL12A; Cytotoxic Lymphocyte Maturation Factor 1, P35; Prev. NKSF1; NK Cell Stimulatory Factor Chain 1; IL-12A; Interleukin-12 Alpha Chain; Interleukin-12 Subunit Alpha; Interleukin 12, P35; CLMF; IL-12, Subunit P35; NFSK; IL35 Subunit; P35; CLMF P35; Interleukin 12A (Natural Killer Cell Stimulatory Factor 1, Cytotoxic Lymphocyte Maturation Factor 1, P35); Natural Killer Cell Stimulatory Factor 1, 35 KD Subunit; Cytotoxic Lymphocyte Maturation Factor 35 KDa Subunit; IL-12 Subunit P35; Interleukin 12A; NF Cell Stimulatory Factor Chain 1; IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40); Natural Killer Cell Stimulatory Factor-2; Natural Killer Cell Stimulatory Factor, 40 KD Subunit; Truncated Interleukin 12B; Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit; IMD29; NK Cell Stimulatory Factor Chain 2; IMD28; Interleukin 12B; Interleukin-12 Beta Chain
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IL-12 beta Protein, Mouse (HEK293, His)
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Cat. No.: HY-P72597
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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Animal-Free IL-12 beta Protein, Human (His)
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Cat. No.: HY-P700100AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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GMP IL-12 Protein, Human (HEK293)
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Cat. No.: HY-P7032G
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12A; Cytotoxic Lymphocyte Maturation Factor 1, P35; Prev. NKSF1; NK Cell Stimulatory Factor Chain 1; IL-12A; Interleukin-12 Alpha Chain; Interleukin-12 Subunit Alpha; Interleukin 12, P35; CLMF; IL-12, Subunit P35; NFSK; IL35 Subunit; P35; CLMF P35; Inte
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IL-12 beta Protein, Rat (HEK293, His)
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Cat. No.: HY-P73164
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cytotoxic Lymphocyte Maturation Factor 2, P40); Natural Killer Cell Stimulatory Factor-2; Natural Killer Cell Stimulatory Factor, 40 KD Subunit; Truncated Interleukin 12B; Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit; IMD29; NK Cell Stimulatory Factor Chain 2; IMD28; Interleukin 12B; Interleukin-12 Beta Chain
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IL-12 beta Protein, Marmoset (HEK293, Fc)
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Cat. No.: HY-P77402
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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Animal-Free IL-12 beta Protein, Mouse (His)
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Cat. No.: HY-P700191AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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Human IL-23 alpha & Mouse IL-12 beta Heterodimer Protein (HEK293, His)
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Cat. No.: HY-P74874
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23A; Interleukin 23, Alpha Subunit P19; Interleukin 23 Subunit Alpha; Interleukin-23 Subunit Alpha; SGRF; Interleukin-23 Subunit P19; IL23P19; IL-23 Subunit Alpha; IL-23A; IL-23p19; IL-23; IL-23-A; P19; JKA3 Induced Upon T-Cell Activation; Interleukin-S
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IL-12 Protein, Rhesus Macaque (HEK293, His)
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Cat. No.: HY-P73897
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12A; Cytotoxic Lymphocyte Maturation Factor 1, P35; Prev. NKSF1; NK Cell Stimulatory Factor Chain 1; IL-12A; Interleukin-12 Alpha Chain; Interleukin-12 Subunit Alpha; Interleukin 12, P35; CLMF; IL-12, Subunit P35; NFSK; IL35 Subunit; P35; CLMF P35; Inte
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IL-12 beta Protein, Rabbit (HEK293, His)
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Cat. No.: HY-P74836
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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IL-12 beta Protein, Mouse (HEK293, Fc)
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Cat. No.: HY-P73162
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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IL-12 beta Protein, Mouse (Biotinylated, HEK293, His-Avi)
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Cat. No.: HY-P78861
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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IL-12 Protein, Mouse (HEK293, Fc)
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Cat. No.: HY-P73157
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: IL12A; Cytotoxic Lymphocyte Maturation Factor 1, P35; Prev. NKSF1; NK Cell Stimulatory Factor Chain 1; IL-12A; Interleukin-12 Alpha Chain; Interleukin-12 Subunit Alpha; Interleukin 12, P35; CLMF; IL-12, Subunit P35; NFSK; IL35 Subunit; P35; CLMF P35; Inte
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IL-12 Protein, Mouse (HEK293, His-Fc)
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Cat. No.: HY-P73158
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: IL12A; Cytotoxic Lymphocyte Maturation Factor 1, P35; Prev. NKSF1; NK Cell Stimulatory Factor Chain 1; IL-12A; Interleukin-12 Alpha Chain; Interleukin-12 Subunit Alpha; Interleukin 12, P35; CLMF; IL-12, Subunit P35; NFSK; IL35 Subunit; P35; CLMF P35; Inte
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IL-12 beta Protein, Mouse (HEK293)
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Cat. No.: HY-P73161
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: IL12B; Interleukin-12 Subunit Beta; Prev. NKSF2; Interleukin 12, P40; IL-12B; IL12, Subunit P40; CLMF2; IL-12 Subunit P40; NKSF; CLMF P40; CLMF; Cytotoxic Lymphocyte Maturation Factor 2, P40; Interleukin 12B (Natural Killer Cell Stimulatory Factor 2, Cyto
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
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Capetin (28-54), human
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- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
